Howard: How'd you get that?
Dr. Lorvis: Easy. Gene Rodenberry needed a vasectomy.
Sheldon: You've snipped Gene Rodenberry's vas deferens?
Dr. Lorvis: Yes.
Howard: Wow, you really went where no man has gone before.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: So you can never take it (the sweater) off?
Leonard: No.
Raj: Not even to sleep?
Leonard: No.
Howard: So you're just an idiot?
Leonard: It's called proving a point.
Howard: Is the point you're an idiot?

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Penny: You locked them in your basement?
Dr. Lorvis: Well, they're not locked in. The door just sticks.
Penny: Okay, so how do they unstick it?
Dr. Lorvis: They'd need the key.

Penny: Okay, you can't just go chasing after every girl who's nice to you.
Dr. Lorvis: Well, that's not what Sheldon says, and he seems to know his way around the ladies.

Leonard: Wow, Donkey Kong. This was my game when I was a kid.
Sheldon: Because it's a story of a pretty blonde girl tirelessly pursued by a small oddly-shaped man?