Leonard: Hey, I am a young man in his sexual prime. Under the right conditions, I am capable of just, really crazy stuff.
Penny: Really? What is the craziest thing you've ever done with a woman? And the time you and I had sex in the ocean does not count.
Leonard: Come on, that's got to count. There was a really strong undertow. We could have died.

Leonard: What would you be if you were attached to another object by an inclined plane, wrapped helically around an axis?
Sheldon: Screwed?
Leonard: There you go.

Leonard: Penny, as a scientist, my job is to figure out why things happen. But I don't think I'll ever understand how someone like me could get to be with someone like you. You know maybe I don't need to understand it, I just need to be grateful. I love you, Penny.

Sheldon: This song is never going to stop. Have you ever dealt with something so relentlessly irritating?
Leonard: That's a trick question, right?

Barry Kripke: Yes, yes, yes. He's a jolly good fellow. What time do the strippers arrive?

Stuart: Okay, I'll go. Howard, when I think about you and Bernadette starting this wonderful life together, I can't help but get a little choked up. I mean, look at you. You have everything. Look at me. I'm 37. I sleep in the back of a comic book store, and I have the bone density of an 80-year-old man. To Howard.

Raj: When I moved to America I was pretty lonely, but when I met Howard my life changed because we could be lonely together.