Howard: Hey guys. I just want everyone to know tonight's not a sad occasion.
Bernadette: Yeah, we just want to have the kind of dinner that we've all had here so many times before.
Howard: Good food. Good friends. And, sometime around midnight, heartburn that makes you pray for death.

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Sheldon: Is it my fault I have a much bigger reputation than he does?
Amy: It's not your fault.
Sheldon: Is it my fault that my name came first on the paper alphabetically?
Amy: Not your fault.
Sheldon: Is it my fault that when the reporter cited me as the lead scientist, I didn't correct him?
Amy: Hey look at that pretty bird.

Howard: All Ma's food is going to be ruined.
Bernadette: Why don't we take it home and put it on our freezer?
Raj: You don't want to do that. Refreezing not only removes moisture, but it creates ice crystals in the fibres of the meat that can compromise its taste and texture. What? I saw a teachable moment. I dropped some culinary science.