Penny: Am I being naive?
Bernadette: I don't know. This is all so new to me. I'm still processing.

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Leonard: You don't go into science for the money.
Bernadette: Speak for yourself. Last month my company both invented and cured restless eye syndrome. Ka-ching, ya blinky chumps!

Sheldon: Hello.
Leonard: Hey, buddy, can we have some privacy?
Sheldon: Of course. Wouldn't want to intrude. (takes red bra out of his pocket and hands it to Penny) This is yours.
Penny: Okay, when I'm done with him, I'm gonna need more information.
Sheldon: Nothing odd. I just wanted to rub Amy's nose in it.

Sheldon: Thankfully all the things my girlfriend used to do can be taken care of with my right hand.

Leonard: I'm not being weird. Am I being weird?
Sheldon: Yes. And that's coming from me.