Wolowitz: Whaddup science bitches?

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Josh: So, I have to ask, was the robot sexy?
Howard: It was actually just a mechanical hand.
Josh: 'Cause that's all you need, right?
Howard: You are my brother.

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Mary: He gets his temper from his daddy.
Leonard: Ah!
Mary: He's got my eyes.
Leonard: I see!
Mary: All that science stuff, that comes from Jesus.

Mary Cooper: You don't hunt, do you?

Mary Cooper: I'm sorry, did I start that sentence with the words, "If it pleases your highness?"