Mrs. Wolowitz: You know what, I'll buy you All-Bran in case you get stopped up in outer space.

Mrs. Wolowitz I'm not going near that fakakta thing. I'll catch a computer virus.
Howard: You can't catch a computer virus.
Mrs. Wolowitz Oh, so now you're an astronaut and a doctor?

Mrs. Wolowitz Howard, it's the phone.
Howard: I know it's the phone, Ma. I can hear the phone.
Mrs. Wolowitz Well who's calling at this ungodly hour?
Howard: I don't know.
Mrs. Wolowitz Well ask them why they're calling at this ungodly hour.
Howard: How can I ask them when I'm talking to you?

Mrs. Wolowitz It's this dress. When I put my front in, my back pops out. When I put my back in, my front pops out. It's like trying to keep two dogs in a bathtub.
Sheldon: What do you want me to do?
Mrs. Wolowitz We're gonna have to work as a team. Get in here, grab a handful and start stuffing.

Amy: Bernadette, I want to thank you for allowing me to be your maid of honor. I also want you to know that I will be happy to do it again if this marriage craps out.

Sheldon: Would you like some aloe vera? 'cause you just got burned.

Amy: Stop it! Today is not about you, it's about Howard and Bernadette, and me!