Bernadette: Sure. I think all branches of science have to move cautiously these days. It's not just giant nuclear weapons that can destroy the world. As a microbiologist, I can tell you even the tiniest organisms can still tear you a new one.
Howard: Interesting. I think what you might need to know about my colleague is that though she claims her field of interest is tiny organisms, she certainly has spent her fair share of time around what we can assume was pretty massive weaponry.
Bernadette: I think Mr. Wolowitz needs to keep in mind that the past is the past. But he should know that I am the kind of girl who could get all the giant missiles she wants.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Howard: What, I'm not hot enough for Angelina Jolie?
Raj: Id like to weigh in here: No.

Amy: Are you in the lanthanide series?
Sheldon: Amy, it's Penny's turn. Penny.
Penny: Uh, I dunno. Are you food?
Sheldon: That's not a apropos! We've already established I'm found on the Periodic Table.
Penny: Well, it's a table, right? I mean, why can't there be food on it?
Sheldon: I knew she wasn't lead car material.

Sheldon: Good morning everyone and welcome to "Science and Society". I'm Dr. Sheldon Cooper, BS, MS, MA, PhD and ScD. OMG, right?