Howard: Thank you for picking us up. There's a warning, right there, on the Scotch bottle. "You cannot be operatin heavy machinery after you had a snootful of this, laddie!"

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: So you can never take it (the sweater) off?
Leonard: No.
Raj: Not even to sleep?
Leonard: No.
Howard: So you're just an idiot?
Leonard: It's called proving a point.
Howard: Is the point you're an idiot?

Bernadette: Maybe we should get one of those machines to help her up the stairs.
Howard: You mean a fork lift?

Barry Kripke: Yes, yes, yes. He's a jolly good fellow. What time do the strippers arrive?

Stuart: Okay, I'll go. Howard, when I think about you and Bernadette starting this wonderful life together, I can't help but get a little choked up. I mean, look at you. You have everything. Look at me. I'm 37. I sleep in the back of a comic book store, and I have the bone density of an 80-year-old man. To Howard.

Raj: When I moved to America I was pretty lonely, but when I met Howard my life changed because we could be lonely together.