Penny: Okay, I want in. Ten bucks says I'll lose interest before that thing stops spinning.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

Amy: What is this?
Sheldon: I'm mapping basic topics of conversation and with whom they can be discussed.
I call these circles "Zones of Privacy". Don't Google that unless you want to see pictures of people's genitals.

Bert: I met her on G-Harmony. That's a Web site for geologists to find love.
Amy: That's a real thing?
Bert: Yeah. Their slogan is "We're all about dating and not the carbon-14 kind".

Sheldon: Two years ago I got my driver's license.
Amy: What? Why didn't you say anything?!
Sheldon: I like being chauffeured around. It makes me feel important.
Amy: So when I got up at 4:00 AM to drive you across the desert to an antique train museum, I didn't have to?
Sheldon: No, you didn't. But keep in mind, I felt extremely important.