Sheldon: I may have lost my guidance system and my girlfriend, but I still have a colon full of yesterday's meals to keep me company. Although, thanks to your high-fiber breakfast, I'm sure that'll be leaving me, too.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Sheldon: And just remember, I am proud of you and I support you in all that you do.
Amy: Thank you. That means a lot.
Sheldon: Oh, and one last thing. If you find yourself working with a male scientist who's as smart as me, as tall as me and has hair like Thor, well, then I want you to step away from the situation and call me immediately.

Raj: I really can't thank you enough for taking me in. You know, I was in a pretty low place in my life, and-
Sheldon: (from across the hall) Oh, Amy, you naughty vixen.
Raj: Anyway, uh, as I was saying, I was at a pretty low place in my life and, uh, if it wasn't for friends like you-
Amy: (from across the hall) My goodness, that form of stimulation is highly efficient.
Raj: I can't compete with that.

Howard: Well, why would you do that?
Colonel Williams: You guys completed phase one, we'll take it from here.
Sheldon: Where did you move it?
Colonel Williams: I can't tell you that.
Leonard: Are you implementing phase two?
Colonel Williams: I can't tell you that.
Sheldon: Wait, so you're just going to take all the work we've done for the last year and toss us aside?
Colonel Williams: That one I can tell you, yes.
Howard: This is all very upsetting.
Colonel Williams: I'm sorry to hear that. As you know, the primary focus of the United States military is people's feelings.
Sheldon: If that's sarcasm, please save it for our enemies.