Penny: Fellas, please.
Howard: Penny, come on, we were just finding our sound.
Penny: You found it. It's the sound of a cat being run over by a lawn mower.

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Sheldon: Woman, you are playing with forces beyond your ken.
Penny: Yeah, well your Ken can kiss my Barbie.

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Beverly Hofstadter: It might explain why the two of you have created an ersatz homosexual marriage to satisfy your need for intimacy.
Howard: Say what?

Leonard: She's only been here a day and a half, and I'm seriously considering alcoholism as a new career path.
Penny: Hey, I talked to her for five minutes yesterday, and I've been half bombed ever since.

Beverly Hofstadter: If you want to have intercourse with that girl, find out what kind of cologne her father wore.