Beverly Hofstadter: It might explain why the two of you have created an ersatz homosexual marriage to satisfy your need for intimacy.
Howard: Say what?

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Howard: So you can never take it (the sweater) off?
Leonard: No.
Raj: Not even to sleep?
Leonard: No.
Howard: So you're just an idiot?
Leonard: It's called proving a point.
Howard: Is the point you're an idiot?

Bernadette: Maybe we should get one of those machines to help her up the stairs.
Howard: You mean a fork lift?

Leonard: She's only been here a day and a half, and I'm seriously considering alcoholism as a new career path.
Penny: Hey, I talked to her for five minutes yesterday, and I've been half bombed ever since.

Penny: I'm curious. What was Leonard like when he was little?
Beverly Hofstadter: I think you mean young. He's always been little.

Beverly Hofstadter: If you want to have intercourse with that girl, find out what kind of cologne her father wore.