Leonard: Hey, Sheldon?
Sheldon: Oh, good. You picked me, you picked me.
Leonard: No, I just got a text from Stuart. Brent Spiner is at the party.
Sheldon: Brent Spiner?
Leonard: Yes.
Sheldon: I don't care.
Leonard: Really? Brent Spiner, Mr. Data himself. You love him.
Sheldon: I did, but I think I've kind of outgrown Star Trek. You know, stock characters, ludicrous plots, beam me up. What a load of hooey.
Leonard: I'm going. Live long and prosper, Sheldon.
Sheldon: Yeah, even that. You look like a dork.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Penny: Wait, what is going on?
Sheldon: In case you have forgotten, Schrodinger's cat is a thought experiment.
Penny: No, no, no, no, I didn't forget. Um, there's this cat in a box and until you open it, it's either dead or alive or both. Although, back in Nebraska, our cat got stuck in my brother's camp trunk, and we did not need to open it to know there was all kinds of dead cat in there.
Amy: Homespun stories, knowledge of physics and a bosom that defies it. You're the whole package, aren't you?

Amy: It's not for us to judge. We're just here to provide comfort and support while you come to grips with what a despicable thing you've done.

Amy: Now Sheldon, I know you're a left handed monkey wrench but you seriously have a mortal enemy
Sheldon: Yes, in fact I have 61. Would you like to see the list?