Howard: To tell you the truth, I'm not really in the mood.
Bernadette: What are you talking about? It'll be fun. All your friends'll be there.
Howard: Yeah, some friends. They all think I'm boring. Maybe you should go without me.
Bernadette: No, if I'm there alone, people might think I'm just a really short person from Avatar.

Howard: I'm sorry I didn't take you to the airport. I just want you to know I'll never forgive myself for being so selfish. And I promise to keep you close for the rest of my life.
Bernadette: Oh, no, that thing's gonna end up in my bedroom.

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Bernadette: Gosh, Amy. I'm sensing a little hostility. Is it maybe because like Sheldon's work, your sex life is also theoretical?

Stuart: Hey. Hey, look at you guys!
Amy: I'm Raggedy Ann, and he's Raggedy C-3PO.
Sheldon: It was a compromise. I lost.

Howard: A week ago, I was an astronaut.
Bernadette: Yeah, well, today you're a Smurf! Keep moving!

Howard: Okay, here it is. Bernadette said you guys are all sick of me talking about my trip to space. Is that true?
Sheldon: Yes.
Raj: No.
Sheldon: We seem to have different approaches here. I was going for helpful honesty. I have no idea what you're doing.
Raj: It's called being nice.
Sheldon: Okay. If you think being nice will get him to shut up, I'll try it.