Mrs. Wolowitz: Howard, what's going on?! Are you boys roughhousing?!
Howard: No, we're not roughhousing! We're scientists! Scientists don't roughhouse!
Mrs. Wolowitz: Excuse me, Mr. Grown-up!

Mrs. Wolowitz I'm not going near that fakakta thing. I'll catch a computer virus.
Howard: You can't catch a computer virus.
Mrs. Wolowitz Oh, so now you're an astronaut and a doctor?

Mrs. Wolowitz Howard, it's the phone.
Howard: I know it's the phone, Ma. I can hear the phone.
Mrs. Wolowitz Well who's calling at this ungodly hour?
Howard: I don't know.
Mrs. Wolowitz Well ask them why they're calling at this ungodly hour.
Howard: How can I ask them when I'm talking to you?

Mrs. Wolowitz It's this dress. When I put my front in, my back pops out. When I put my back in, my front pops out. It's like trying to keep two dogs in a bathtub.
Sheldon: What do you want me to do?
Mrs. Wolowitz We're gonna have to work as a team. Get in here, grab a handful and start stuffing.

Sheldon: Oh, Stuart, good. I was wondering, will you be accepting Bitcoin?
Stuart: Well, I don't know what that is, but it's got "coin" in it, and my cash register doesn't, so yeah.

Mrs. Wolowitz: Howard, I made cookies for you and your little friends!
Howard: They're not my little friends, and we don't want cookies!
Leonard: Actually, a cookie sounds good.
Howard: All right, we'll have cookies! Thank you very much!

Penny: Leonard thinks when we broke up, it didn't bother me.
Zack: That's crazy. When we were going out, she used to talk about you all the time. In fact, I think she only dated me because I reminded her of you.
Leonard: Sure. Because we're both people?
Zack: Damn right we are.