Penny: No. Sweetie, you shouldn't do things that make you feel bad.
Leonard: Well, I'm doing this.
Sheldon: And of course he is. He is a textbook satisficer.
Leonard: That's not even a word.
Sheldon: Uh, yes, it is. According to Nobel Prize-winning economist Herbert Simon, satisficing is a decision-making strategy whereby a person accepts whatever available option is satisfactory rather than seeking out a course of action that would make him happiest, as I just did when I explained what satisficing was.
Raj: He's right. No one wanted to hear that. He knew it, yet he plowed ahead.

President Siebert: Look, the Nobel Committee doesn't like infighting, so if the four of you don't stop sniping at each other, the award's gonna go to someone else entirely.
Amy: He's right. You know, like it or not, we can't avoid each other. Let's at least try to be civil.
Drs. Campbell: Agreed. You know, when you think about it, we're linked together the same way that super-asymmetry links together every atom in the universe.
Dr. Pemberton: Hmm.
Amy: That's not what it does at all!
Dr. Pemberton: Well, that's the great thing about science. We all get to have our own opinions.
Sheldon: I'm still not talking. That's impressive, right?

Sheldon: Ah, Beverly, there you are.
Beverly Hofstadter: Sheldon, how nice to see you. Leonard was just showing me his new lab.
Sheldon: Oh, yes, experimental physics, the carpentry of the science world.

Sheldon: What? No knock? What's the fracas?

Amy: It's weird. I don't really feel different, but I guess our lives will never be the same.
Sheldon: Oh, I don't know. We're going to work like always. I still put my pants on both legs at a time.
Amy: One day that's gonna end very badly.

Sheldon: How did you get down here?
Penny: The elevator. It's really fast.
Sheldon: I-I need to be alone right now. Don't try to follow me.
Penny: All right. You need a ride?
Sheldon: That'd be great. Thank you.

Amy: I think you need to do some editing, like maybe cut out all that stuff about your childhood.
Sheldon: Are you kidding? Growing up in the backwoods of East Texas is what makes me warm and relatable.
Amy: Well, what about all these pages calling out everyone who said you wouldn't succeed?
Sheldon: I told them all they would rue the day. How is it gonna make me look if the day finally comes, and they're not filled with rue?

Sheldon: Does this mean you're not going to sing Soft Kitty?
Mary: No, I will always sing you Soft Kitty. [sings] Soft kitty, warm kitty, little ball of fur…
Leonard: [opens door] Mrs. Cooper, were we supposed to take that pie out of the oven?
Sheldon: Get out!
Mary: Well, that was rude.
Sheldon: Well, I know, but he means well. Sing.
Mary: [sings] Happy kitty, sleepy kitty…
Sheldon: What are you trying to pull, Mom? From the top.
Mary: [to God] This is what I'm talking about. [sings] Soft kitty, warm kitty, little ball of fur…

[Sheldon moves around the movie theater, sitting in various seats and emitting various noises]
Steph: What is he doing?
Leonard: He's finding the "acoustic sweet spot".
Steph: Does he always do this?
Leonard: Sometimes he brings a toy xylophone. I am really sorry about this.
Steph: No, it's fine. You know, he's sweet.
Sheldon: My apologies, you've been sitting in it all along. Leonard, you want to slide over one?
Leonard: No, just sit here.
[As the movie begins, Sheldon cranes his neck over to experience the sound in Leonard's seat]
Sheldon: Oh, yeah, this is it.

Penny: I meant has he ever been involved with someone who wasn't a brainiac?
Sheldon: Oh! Well, a few years ago, he did go out with a woman who had a Ph.D in French Literature.
Penny: How is that not a brainiac?
Sheldon: Well, for one thing she was French.

Sheldon: Whenever you're ready, AT&T!

Sheldon: You're in my bedroom.
Penny: Yeah, Leonard gave me an emergency key.
Sheldon: People can't be in my bedroom.

Sheldon: I'm hell-bent on catching a cyber criminal, not the common cold.

Penny: No, I can't. Sheldon, honey, I don't want things to be weird between us.
Sheldon: Won't it also be 'weird' if I have to say hello to you every morning on my way to work and you're living in a refrigerator box and washing your hair with rainwater?

Sheldon: Howard, I'm gonna need another mandarin lesson, I obviously didn't make my point with those people.
Howard: For God's sake, Sheldon, if you don't like the tangerine chicken, don't order the tangerine chicken.
Sheldon: I like tangerine chicken, I'm just not getting tangerine chicken.