Bernadette: I can't believe this is how you thank me.
Penny: I thanked you by thanking you. And I sent you that fancy box of pears.
Bernadette: What am I supposed to do with 20 pears? Have a pear party?

Bernadette: I had a plan. I kept leaving Dove bar wrappers around to explain any weight gain.
Amy: Where did you get empty Dove bar wrappers?
Bernadette: From all the Dove bars I ate! I'm pregnant! Try to keep up!

Stuart: Oh, so she's good enough for Howard but not for me?
Howard: Yeah.
Bernadette: Yeah. Go have weird relationships with your own mother and cousin. This is his turf.

Leonard: You don't go into science for the money.
Bernadette: Speak for yourself. Last month my company both invented and cured restless eye syndrome. Ka-ching, ya blinky chumps!

Stuart: Where are the kids?
Howard: I thought they were with you.
Stuart: What? No!
Howard: I'm kidding. They're at daycare.
Stuart: What about me makes you think my heart can handle that joke?

Leonard: Just tell me the truth, Mother. Was my whole childhood just one big experiment?
Beverly Hofstadter: Of course not, dear. It was thousands of small experiments.
Leonard: So that's all I was to you, a-a test subject?
Beverly Hofstadter: No, you were my baby and I found you fascinating.
Leonard: Really?
Beverly Hofstadter: Yes, watching you develop, tracking your progress. I know I'm not the warmest of parents, but it was time we spent together, and, honestly, those are some of my fondest memories.
Leonard: When did you stop?
Beverly Hofstadter: Oh, I can't tell you. The experiment isn't over.

Raj: I never thought I would see Sheldon enjoying himself around babies so much.
Amy: Yeah, how about that?
Raj: So he just happened to stumble upon a book about experimenting with them the same day we were hanging out with Howard's kids?
Amy: Yep, don't overthink it.