Marty: Howard, why is he yelling at me?
Sheldon: All right, you were on Jeopardy. Allow me to Alex Trebek this and put it in the form of a question: Who has been a complete waste of our time?
Howard: Marty, let me call you back.
Leonard: Someday, when I'm up on murder charges, you'll be hearing from me.
Sheldon: You don't need him. I'll represent you.

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Bernadette: I had a plan. I kept leaving Dove bar wrappers around to explain any weight gain.
Amy: Where did you get empty Dove bar wrappers?
Bernadette: From all the Dove bars I ate! I'm pregnant! Try to keep up!

Bernadette: Do you know what? It's just a research project. The most important job in the world is gonna be raising this child. It's all I need to give my life meaning.
Penny: Oh, that's so beautiful.
Bernadette: You believe me? Oh, good. Eleven more chumps like you, I'll have the jury eating out of my hand.

Sheldon: I don't understand why I can't talk at this meeting.
Leonard: 'Cause when you talk, it enrages people.