Mary Cooper: Shelly, how do I put this? By your third birthday, you had memorized over a thousand different kinds of trains, and I never imagined a woman getting aboard any of them.
Sheldon: What, so - You thought I was going to be alone for the rest of my life?
Mary Cooper: No! Just for the middle part. 'Cause at the end I assumed there'd be nurses.

Amy: Well, uh, Howard and Bernadette had their baby.
Mary Cooper: (gasps) Oh, that's wonderful! Now, have they decided to raise it Jewish or regular?
Sheldon: Welcome to Texas.

Mary: He gets his temper from his daddy.
Leonard: Ah!
Mary: He's got my eyes.
Leonard: I see!
Mary: All that science stuff, that comes from Jesus.

Mary Cooper: When your mom gets back, I'm gonna need to apologize for the way I spoke to her.
Penny: Well, come on, she did kinda start it.
Mary Cooper: Doesn't matter. A good Christian would have turned the other cheek. On the other hand, a good Texan would have shot her, so I'll just split the difference.

Amy: Well, uh, Howard and Bernadette had their baby.
Mary Cooper: (gasps) Oh, that's wonderful! Now, have they decided to raise it Jewish or regular?
Sheldon: Welcome to Texas.

Bernadette: Everyone's a better mom than me.
Raj: Oh, don't take it so personally, maybe your baby's just a jerk.

Mary Cooper: Sheldon, if you're trying to prove me wrong, the tighty-whities on your head ain't changing my mind.