Amy: He's been in there a long time. Should I go talk to him?
Mary Cooper: He's upset with me. I should be the one who talks to him. (stays seated and works on her knitting)
Amy: Are you going to?
Mary Cooper: Oh, heck no.

Mary: He gets his temper from his daddy.
Leonard: Ah.
Mary: He's got my eyes.
Leonard: I see.
Mary: All that science stuff, that comes from Jesus.

Sheldon: Well, this is confusing for me. But I don't want to stand in the way of your happiness. So, I will condemn you internally while maintaining an outward appearance of acceptance.
Mary: That is very Christian of you.

Sheldon: I'd like you to meet Oppenheimer, Frisch, Panofsky, Feynman, Weisskopf.
Mary: Yeah, I get it. You got a lot of cats, and you gave 'em cute Jewish names.

Bernadette: Everyone's a better mom than me.
Raj: Oh, don't take it so personally, maybe your baby's just a jerk.

Amy: Well, uh, Howard and Bernadette had their baby.
Mary Cooper: (gasps) Oh, that's wonderful! Now, have they decided to raise it Jewish or regular?
Sheldon: Welcome to Texas.

Mary Cooper: Sheldon, if you're trying to prove me wrong, the tighty-whities on your head ain't changing my mind.