Penny: Okay, Sheldon, you don't have to do this because Leonard and I are not-
Leonard: Are you sure you want to include him in this?
Sheldon: Include me in what? Is there a plot afoot? I'll have no truck with plots.
Penny: No, you're right. No, there's no plots, no trucks, no feet.

Leonard: Poor Mr. Fowler, I really feel sorry for the little guy.
Penny: I know. After they had Amy, she should've just eaten him and been done with it.
Leonard: Look at you retaining facts from a nature show.

Raj: I came here for your support.
Leonard: Well, then, you just walked up three flights of stairs for nothing.
Penny: Wait, don't you mean four flights?
Leonard: No, it's actually three.
Penny: But we're on the fourth floor. I mean, you have the lobby, first floor, second, third, fourth.
Leonard: The lobby's the first floor, so lobby, second, third, fourth.
Penny: That does not seem right.

Penny: So neither of them showed up for work today?
Leonard: No, I tried calling and no one picked up.
Penny: Look, I'm sure they're fine. They were probably up all night coming up with a new theory.
Leonard: I also texted to see if he wanted to go to the new Fantastic Beasts movie and he didn't respond.
Penny: All right, well, they're already dead. There's nothing we can do.

Penny: All right, I take Bernadette.
Howard: Really? You're picking her over me?
Penny: Yeah, 'cause she's vicious and can hide behind a mushroom.

Leonard: Don't make it sound childish. It's the scientific word for dust.
Penny: What was wrong with "dust"?

Leonard: Sheldon, that was really rude.
Sheldon: I'm sorry. Amy is the one constant I can count on, and now she's changing.
Leonard: It's just a haircut and some clothes.
Sheldon: No, it's the last straw! I can't take any more! [elevator bell dings]
Penny: Can you believe it? They finally fixed the elevator.

Sheldon: Leonard we need to do something about your wife.
Leonard: What's the matter?
Sheldon: She is clearly sick, and she's gonna take us all down with her.
Leonard: She's not sick, Sheldon.
Sheldon: She is, and I'm gonna catch it, and it's gonna ruin the greatest day of my life.
Leonard: I promise you're not going to get what she has.
Penny: What's going on?
Sheldon: [gasps] Unclean! Unclean!
Penny: What?
Leonard: He thinks you're sick.
Penny: Oh. Should we tell him?
Leonard: Well, if we don't, he might try and jump out of the plane.
Penny: Yeah. Doesn't answer my question.

Leonard: Okay, listen to me, this is just a minor setback.
Penny: No, it's not, okay? I've been out here for, like, ten years. I've nothing to show for it.
Leonard: Well, you have me.
Penny: You're right. I do have you. Mm. Let's get married.
Leonard: What?
Penny: Ooh. Leonard Hofstadter, will you marry me?
Leonard: Um…
Penny: Did you seriously just say um?
Leonard: Look, you know I love you but, but you're, you're drunk and sad and feeling lost.
Penny: Okay, so, so you don't want to marry me?
Leonard: That is not what I said.
Penny: No, forget it. I take it back. Offer's off the table.

Penny: Sing Soft Kitty to me.
Sheldon: Soft Kitty is for when you’re sick. You're not sick.
Penny: Injured and drugged is a kind of sick.
Sheldon: [sings] Soft kitty, warm kitty, little ball of fur…
Penny: Wait, wait. Let's sing it as a round. I'll start. [sings] Soft kitty, warm kitty, little ball of fur… See that's where you come in. I'll start over. [sings] Soft kitty, warm kitty, little ball of fur… I've got all night, Sheldon. Soft kitty, warm kitty…
Both: [sing] ...little ball of fur, happy kitty, sleepy kitty, purr, purr, purr.

Penny: Come on, I mean, you're not upset that your marriage is over?
Beverly: Well, initially I felt something akin to grief and perhaps anger, but that's the natural reaction of the limbic system to being betrayed by a loathsome son of a bitch.
Penny: Sure, sure.

Penny: I like hanging out with you guys, but I'm not gonna apologize for something I didn't do.
Leonard: Well, actually, technically, you did do it.
Penny: That's strike one, Leonard.

Sheldon: You have to drive me to work.
Penny: Yeah, I really don't think I do.
Sheldon: But I don't drive and I can't take the bus.
Penny: Alright, honey, you'll be fine as long as you don't do that bungee chord thing.

Penny: Well we're in Vegas. I want to go downstairs, get a bucket of margaritas, dance until I vomit all over a roulette wheel and watch it go everywhere.
Amy: What if we don't want to vomit?
Penny: Oh, you will. That's why they give you the bucket.

Penny: I have to go to the bathroom.
Sheldon: Can't you hold it?
Penny: Not for 2600 years!