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Quote from Sheldon in the episode The Jiminy Conjecture

Raj: I don't like bugs, okay. They freak me out.
Sheldon: Interesting. You're afraid of insects and women. Ladybugs must render you catatonic.

Quote from Sheldon in the episode The Lizard-Spock Expansion

Sheldon: Scissors cuts paper, paper covers rock, rock crushes lizard, lizard poisons Spock, Spock smashes scissors, scissors decapitates lizard, lizard eats paper, paper disproves Spock, Spock vaporizes rock, and as it always has, rock crushes scissors.

Quote from Howard in the episode The Tangerine Factor

Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Quote from Sheldon in the episode The Gorilla Experiment

Sheldon: Why are you crying?
Penny: Because I'm stupid.
Sheldon: That's no reason to cry. One cries because one is sad. For example, I cry because others are stupid, and that makes me sad.

Quote from Stuart in the episode The Hofstadter Isotope

Stuart: Oh, Sheldon, I'm afraid you couldn't be more wrong.
Sheldon: More wrong? Wrong is an absolute state and not subject to gradation.
Stuart: Of course it is. It's a little wrong to say a tomato is a vegetable, it's very wrong to say it's a suspension bridge.

Quote from Penny in the episode The Itchy Brain Simulation

Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Quote from Sheldon in the episode The Griffin Equivalency

Howard: Sheldon, don't take this the wrong way, but, you're insane.
Leonard: That may well be, but the fact is it wouldn't kill us to meet some new people.
Sheldon: For the record, it could kill us to meet new people. They could be murderers or the carriers of unusual pathogens. And I'm not insane, my mother had me tested.

Quote from Raj in the episode The Santa Simulation

Raj: Oh man, first monster I see I'm gonna sneak up behind him, whip out my wand and shoot my magic all over his ass!
Stuart: Do you hear yourself when you say these things?

Quote from Amy in the episode The Opening Night Excitation

Amy: Okay, what is going on?
Penny: We just want you to be prepared for any surprises that could happen tomorrow.
Amy: What surprises?
Bernadette: We don't want to spoil anything, but you should know that Sheldon said he's ready to be physical.
Amy: You shut your damn mouth! You actually heard him say this?
Penny: Yes, he said he wants to do something to show you how much you mean to him.
Amy: I can't believe it. I don't know what to say.
Bernadette: Well, we're really happy for you and we know how much-
Amy: I do know what to say. Let's get me waxed!

Quote from Sheldon in the episode The Separation Oscillation

Amy: I've seen and talked to you more in the two days we've been broken up than in the last two months we were together.
Sheldon: Well, if you want to see less of me, maybe we should go out again.

Quote from Raj in the episode The Clean Room Infiltration

Raj: Amy, good luck getting these guys excited about a dinner with a theme. I gave up when no one cared about my Tom Hanks-Giving.

Quote from Penny in the episode The Leftover Thermalization

Penny: I mean, who even reads Scientific American?
Leonard: It's kind of a big deal.
Penny: If it's such a big deal, how come the biggest celebrity they could get for the cover is a molecule?

Quote from Sheldon in the episode The Septum Deviation

Amy: This is an easy one. You love this guy.
Sheldon: Me.
Amy: Come on. He's an under appreciated genius.
Sheldon: Still think it's me.
Amy: It's not you. Now think, there's a car named after him.
Sheldon: Of course there is. The Mini Cooper because it's me.
Amy: How about this? He's a poor man's Sheldon Cooper.
Sheldon: Oh, Tesla.

Quote from Mrs. Wolowitz in the episode The Habitation Configuration

Mrs. Wolowitz: Howard, help, my hand's stuck in the garbage disposal.
Howard: Let go of whatever piece of food you're holding.
Mrs. Wolowitz: Are you kidding? It's a perfectly good chicken leg.

Quote from Penny in the episode The Vacation Solution

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.

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