Sheldon: I need your help in a matter of semiotics.
Penny: What?
Sheldon: Semiotics, the study of signs and symbols as a branch of the philosophy related to linguistics.
Penny: Okay, honey, I know you think you are explaining yourself, but you're really not.
Sheldon: Can't we just go to Big Boy? They only have one burger: the Big Boy.
Penny: The Barbecue Burger is like the Big Boy.
Sheldon: Excuse me, in a world that already includes a Big Boy, why would I settle for something that's like a Big Boy?
Sheldon: (At The Cheesecake Factory) Who do I speak to about permanently reserving this table?
Penny: I don't know, a psychiatrist?
Leslie: Come for the breasts, stay for the brains!