Raj: Oh, uh, come in, come in. Oh, I, uh, I didn't think I was going to get to see you until tomorrow.
Howard: Yeah, well, Bernadette's a little under the weather and my mom's kind of under my dentist.
Raj: Wait, your, your mother is sleeping with your dentist?
Howard: Former dentist. I need a new one now that I know where his hands have been.

Raj: So you're wandering all around by yourself? That's not the kind of hero's welcome an astronaut should come home to.
Howard: It's okay. You know, we space cowboys don't do what we do for glory and fame. We leave that to your rock stars and your athletes and your Howie Mandels.

Sheldon: Oh, ow, blueberry in my nose, blueberry in my nose!
Leonard: Snort it down and keep eating!

Stuart: "To Stuart, your comic book store is out of this world. Just like the guy in this picture was."
Sheldon: For the record, he also thinks Walgreens and the dry cleaners are out of this world.
Howard: That's not true. At Walgreens I was over the moon for their store-brand antacids.

Bernadette: I just think in relationships you get back what you put into them.
Amy: That's not always true. Last night, I gave Sheldon my best come-hither look, and he responded by explaining how wheat came to be cultivated.

Amy: I think I'm gonna try green tea mixed with lemon zinger.
Sheldon: Two tea bags in one cup? You're not at a rave.

Sheldon: Couples costumes are one of the few benefits of being in a relationship. Now imagine this, you and I entering Stuart's party and all eyes turn to see America's most beloved and glamorous couple.
Amy: Yeah?
Sheldon: R2-D2 and C-3PO. Dibs on 3PO.

Sheldon: How about one of the most beguiling and influential couples of the 20th century? Hewlett and Packard. Dibs on Hewlett.
What? You want to be Hewlett?

Penny: So, what ya doing? Better not be building a robot girlfriend.
Leonard: No. Although Howard was making some real strides in that area until he met Bernadette.
Penny: You're kidding.
Leonard: Nope. Now the Lisatronic 3000 just sits in a box waiting for the phone to ring.

Leonard: It's kind of crazy. I've never fooled around in the lab before.
Penny: Really? Never?
Leonard: No. I did have a shot with the Lisatronic, but the extension cord wasn't long enough.

Leonard: Oh, you don't have any jewelry on, do you?
Penny: No. Why?
Leonard: A grad student forgot to take out one of his piercings. Now he's on a transplant list waiting for a nipple his size.

Sheldon: A Tardis makes no sense. It's a time machine from a science-fiction show. it has nothing to do with Halloween. That being said, if you don't get a Tardis, you stink and your party stinks.

Raj: Hey, Stuart, I see you're getting ready for your Halloween party.
Stuart: Yeah, it's my annual attempt to meet women. Ninth time's the charm.

Raj: You know, you don't worry about money. Ill take care of everything.
Stuart: Really?
Raj: Yeah, youll love it. Ain't no party like a Koothra-party.

Howard: But you know what wasn't a party? That hotel in Kazakhstan they put you up in before the launch. I mean, it's your last night on Earth. You'd think you'd get one porn channel.
Leonard: Have you noticed that Howard can take any topic and use it to remind you that he went to space?
Sheldon: Interesting hypothesis. Let's apply the scientific method, perform an experiment.
Leonard: Okay. Hey, Howard, any thoughts on where we should get dinner?
Howard: Anywhere but the Space Station. On a good day, dinner was a bag full of meat loaf. But, hey, you dont go there for the food, you go there for the view.
Sheldon: It's fascinating. Let me see if I can duplicate the result. Howard, I've always thought the lemon was an underrated fruit. Care to weigh in?
Howard: Not really.
Sheldon: Oh, well.
Howard: You know, people say the Soyuz capsule was a lemon. But, hey, that baby got me to space and back.