Leonard: We might want to live together.
Sheldon: Oh. Well, I've already given this some thought. And I'm willing to let Penny live with us, one day a week for a trial period. Now, obviously not when she's made cranky by the shedding of her uterine lining.

Beverly Hofstadter: Hello, Leonard.
Leonard: Hi, mom. I have some exciting news.
Beverly Hofstadter: I'm listening.
Leonard: Before I tell you, will you promise to try and be happy for me and keep any concerns you have to yourself?
Beverly Hofstadter: No.

Leonard: It's nice that you called them esteemed.
Sheldon: You're right, I'll take that out.

Sheldon: [President Siebert said] that everybody has to do things they don't want to do. He then gave an example of something he had to do although he didn't want to. And that was look at my stupid face.
Leonard: That's a rude thing to say ... out loud.

Amy: Maybe you'll like living alone.
Sheldon: Perhaps.
Amy: And if you don't, maybe you and I could live together.
Sheldon: Oh, sure! While we're at it, why don't we get engaged, too? Why don't we get a little house, start a family, enjoy our sunset years together? Do you hear yourself woman?!

Sheldon: Can you break a twenty?
Stuart: No, I only have hundreds.
Sheldon: You know what. I don't always recognize sarcasm, but I do right now and I don't appreciate it. I'm sorry for your loss, but you're not the only one whose day's been a disaster.

Stuart: I don't mean to be rude, Sheldon, but my life is kinda falling apart right now.

Leonard: You know he can't take a trip like this by himself.
Penny: He's a grown man.
Leonard: No, he looks like a grown man. You've seen Freaky Friday, sometimes little kids end up in big person bodies.

Sheldon: I'm writing an appeal to the faculty senate so that I can move on from string theory.
Leonard: How's it going?
Sheldon: You tell me. "Dear esteemed colleagues. As you may know, I have requested to change my field of study. My decision to do so is, I believe, in the best interest of science. At your convenience, I'd be happy to explain it to you in words you'll understand."

Sheldon: And by the way, I saw you make this Strawberry Quik with syrup. You're supposed to use the powder.
Amy: It tastes the same.
Sheldon: No, the syrup tastes better and I don't like it.

Raj: Boy, I'm so hungry today. I wonder why.
Howard: Because you had sex the other night?
Raj: You know what, that might be it. By the way, it isn't like riding a bike. I fell off a few times.

Sheldon: You tracked my phone?
Leonard: Yeah.
Sheldon: Boy, you chase one balloon for three miles.
Penny: We were worried about you.
Sheldon: Don't be melodramatic. I'm just getting on a train and leaving for ever.

Beverly Hofstadter: Leonard, would it make you feel better to hear that your mother approved of your life choices?
Leonard: Yes, it would.
Beverly Hofstadter: Yeah. Well, you should work on that.

Howard: Hang on, I know a place where you could you stay and earn some money at the same time.
Stuart: Great!
Howard: I just have to warn you: it will involve humiliation, degradation and verbal abuse.
Stuart: So, what's the catch?

Sheldon: It's an outrage. Honestly, I am tempted to leave the university.
Howard: You know, if you're really serious about that I hear there are some exciting opportunities in home care for the old and fat.