Sheldon: Can I get you anything else?
Amy: No, thanks. I think I'm good.
Sheldon: You sure? There's still plenty of pork fat. Although, if we don't eat it, I suppose we could turn it into soap.
Amy: That might taste better.

Sheldon: Oh, and speaking of Valentine's Day, I haven't forgotten about you tonight.
Amy: What do you mean?
Sheldon: Well, you've become such an integral part of my life as well as this show, I felt it only right to include your name in the title.
Amy: Oh, that is so sweet.
Sheldon: So from now on, this program will be officially known as Dr. Sheldon Cooper and Dr. Amy Farrah Fowler present Dr. Sheldon Cooper's Fun With Flags.
Amy: Catchy.

Bernadette: It would mean so much if you would be the maid of honor at my wedding.
Amy: What? Wait is this some kind of practical joke? Like in Norway when my "friends" trapped me in a sauna with a horny otter?

Amy: I don't object to the concept of a deity, but I'm baffled by the notion of one that takes attendance.

Amy: And action.
Wil Wheaton: And cut! You realize I'm doing this for free, right?
Amy: Yes, and so far we're still not getting our money's worth.

Amy: Why can't they do something sensible like Sheldon, and start their own comic book convention? Also, who wants to throw me out that window?

Amy: Sheldon, the point is Wil learned to embrace that part of his life and moved on to bigger and better things.
Wil Wheaton: Yeah, I'm an author now, I do public speaking and I have my own web series about board games.
Amy: (To Wil) We're trying to cheer up him.

Amy: Stop it! Today is not about you, it's about Howard and Bernadette, and me!

Penny: Wait, what is going on?
Sheldon: In case you have forgotten, Schrodinger's cat is a thought experiment.
Penny: No, no, no, no, I didn't forget. Um, there's this cat in a box and until you open it, it's either dead or alive or both. Although, back in Nebraska, our cat got stuck in my brother's camp trunk, and we did not need to open it to know there was all kinds of dead cat in there.
Amy: Homespun stories, knowledge of physics and a bosom that defies it. You're the whole package, aren't you?

Amy: Wow. Déjà vu.
Sheldon: Amy, you're a neuroscientist. you know the latest research into déjà vu suggests it's nothing but the frontal regions of the brain attempting to correct an inaccurate memory.
Amy: You telling me stuff I already know is definitely déjà vu.

Sheldon: How can I tell if I'm doing something for a noble reason or a selfish reason?
Amy: Try saying the thing in your head and see if you can add the words, "That'll show 'em."

Sheldon: Did Bernadette even try to send us a sewing kit?
Amy: She did. Amazon, standard shipping, not even Prime.
Sheldon: (gasps) We could've done that ourselves.
Amy: (chuckles) That's what she said.

Penny: Look, I know this is your wedding, and you can do whatever you want, but if you think anyone but me is gonna be your maid of honor, then you're an idiot because you are my best friend.
Howard: Too late, Bernade-
Amy: (pushes Howard out of the way, rushes to hug Penny) Bestie!

Bernadette: How was your prom? Did you go?
Amy: No, but I was on cleanup crew.
Penny: Aw, that's sad.
Amy: No, it was okay. The DJ let me dance one slow dance with my mop before he shut down. Whenever I see a bucket of dirty water, I still hear Lady in Red.

Sheldon: Is it my fault I have a much bigger reputation than he does?
Amy: It's not your fault.
Sheldon: Is it my fault that my name came first on the paper alphabetically?
Amy: Not your fault.
Sheldon: Is it my fault that when the reporter cited me as the lead scientist, I didn't correct him?
Amy: Hey look at that pretty bird.