Amy: You better watch that attitude, buddy. You're dating the popular girl now.

Penny: Wait, what is going on?
Sheldon: In case you have forgotten, Schrodinger's cat is a thought experiment.
Penny: No, no, no, no, I didn't forget. Um, there's this cat in a box and until you open it, it's either dead or alive or both. Although, back in Nebraska, our cat got stuck in my brother's camp trunk, and we did not need to open it to know there was all kinds of dead cat in there.
Amy: Homespun stories, knowledge of physics and a bosom that defies it. You're the whole package, aren't you?

Amy: Stop it! Today is not about you, it's about Howard and Bernadette, and me!

Amy: I don't object to the concept of a deity, but I'm baffled by the notion of one that takes attendance.

Amy: Seriously, is that tape? Like, how are they staying up like that?

Amy: Sheldon, the point is Wil learned to embrace that part of his life and moved on to bigger and better things.
Wil Wheaton: Yeah, I'm an author now, I do public speaking and I have my own web series about board games.
Amy: (To Wil) We're trying to cheer up him.

Amy: Why can't they do something sensible like Sheldon, and start their own comic book convention? Also, who wants to throw me out that window?

Amy: I'm not surprised you want to end the relationship. I'm a little surprised you didn't get AppleCare.

Amy: It actually sounds like he's doing pretty well.
Penny: I really think this is going to be for the best.
Leonard: Me too. And he was able to take a sabbatical -
*Amy starts hitting Leonard with a pillow*
Amy: How could you let him go!?

Bernadette: How was your prom? Did you go?
Amy: No, but I was on cleanup crew.
Penny: Aw, that's sad.
Amy: No, it was okay. The DJ let me dance one slow dance with my mop before he shut down. Whenever I see a bucket of dirty water, I still hear Lady in Red.

Sheldon: The truth is, I can no longer balance a full time career, a popular Internet show, and a girlfriend.
Amy: And he really does have one, you jerks on the comment board.

Amy: Scavenger hunts at Harvard were really tough. I always got stuck on the first challenge, trying to find someone to be on a team with me. I guess that story's more sad than funny.

Sheldon: Is it my fault I have a much bigger reputation than he does?
Amy: It's not your fault.
Sheldon: Is it my fault that my name came first on the paper alphabetically?
Amy: Not your fault.
Sheldon: Is it my fault that when the reporter cited me as the lead scientist, I didn't correct him?
Amy: Hey look at that pretty bird.

Sheldon: Oh, and speaking of Valentine's Day, I haven't forgotten about you tonight.
Amy: What do you mean?
Sheldon: Well, you've become such an integral part of my life as well as this show, I felt it only right to include your name in the title.
Amy: Oh, that is so sweet.
Sheldon: So from now on, this program will be officially known as Dr. Sheldon Cooper and Dr. Amy Farrah Fowler present Dr. Sheldon Cooper's Fun With Flags.
Amy: Catchy.

Amy: I got here as quickly as I could.
Sheldon: You're too late.
*Sheldon plays "Taps" and drapes a cloth over his laptop."
Amy: Sheldon, this is silly.
Sheldon: You got emotional when that lab monkey died.
Amy: That lab monkey told me he loved me in sign language.