Howard: You know, I'm really glad you decided to learn Mandarin.
Sheldon: Why?
Howard: Once you're fluent, you'll have a billion more people to annoy instead of me.

Josh: So, I have to ask, was the robot sexy?
Howard: It was actually just a mechanical hand.
Josh: 'Cause that's all you need, right?
Howard: You are my brother.

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Howard: I invented a game. Want to play?
Leonard: Sure.
Howard: It's called Emily or Cinnamon. I give you actual quotes I've heard Raj say, and you guess if he was talking to his girlfriend or his dog.

Howard: So you can never take it (the sweater) off?
Leonard: No.
Raj: Not even to sleep?
Leonard: No.
Howard: So you're just an idiot?
Leonard: It's called proving a point.
Howard: Is the point you're an idiot?

Bernadette: Does your mother call you every day at work to see if you had a healthy lunch?
Howard: My mother calls me every day at work to see if I had a healthy bowel movement.

Howard: Sheldon, you're a condescending jerk. Why on earth would I want to do something nice for you?
Sheldon: To go to Jewish heaven.
Howard: Jews don't have heaven.
Sheldon: To avoid Jewish hell?
Howard: Have you met my mother? I live in Jewish hell.

Penny: (Whispers) Here she comes.
Howard: Smart. Whisper so the deaf chick doesn't hear you!

Wolowitz: Penny, let me take this opportunity to point out that you are looking particularly ravishing today.
Penny: Not with a thousand condoms, Howard.
Wolowitz: So there is a number.

Raj: We have to go over some ground rules about Emily.
Howard: Like when it turns out she's made of rubber, I don't say anything?
Raj: She's very real.
Howard: That's what it says on the box. Right next to dishwasher safe.

Leonard: OK, is everyone clear on the plan?
Howard: Yes, Koothrappali's going to wet himself, I'm gonna throw up, Sheldon's gonna run away and you're going to die. Shall we synchronize our watches?

Stuart: I'm not bringing your mother. I have a date.
Howard: Oh, so now you're cheating on my mother.

Mrs. Wolowitz: Want me to get you a popsicle?
Howard: Cherry, please!
Mrs. Wolowitz: I ate the cherry. All that's left is green.
Howard: You make me wanna kill myself!

Bernadette: Maybe we should get one of those machines to help her up the stairs.
Howard: You mean a forklift?

Wolowitz: If it's "creepy" to use the Internet, military satellites, and robot aircraft to find a house full of gorgeous young models so I can drop in on them unexpected, then fine, I'm "creepy".