Penny: That's amazing.
Sheldon: I wouldn't say amazing. At best it's a modest leap forward from the basic technology that gave us Country Bear Jamboree.
Howard: Hey, Sheldon? Ahem.
Sheldon: Yes?
*Howard commands the robot arm to perform a hand gesture*
Sheldon: Peace?
Howard: No, not peace. Hang on.

Sheldon: Of all the overrated physicists in all the labs in all the world, why does it have to be Leslie Winkle?

Sheldon: Just because your career's been stagnant for a few years, that's no reason to give up.

Sheldon: You sounded in distress. I was worried something unpleasant was happening to you, like a murder or spontaneous coitus with Leonard.

Sheldon: We're scientists, we can conduct our own research. I propose that we imprison two street people-
Amy: No.
Sheldon: You didn't even let me finish.
Amy: Forget it.
Sheldon: Oh, so you can experiment on all the apes you want, but I want to manipulate the emotions of two captive human beings, suddenly I'm the monster.

Sheldon: I also was certain HD-DVD would win out over Blu-ray.
Amy: How old were you then?
Sheldon: Old enough to know better!

Sheldon: As a Texas gentleman, I'm inclined to say ladies first. Although, I'm concerned that level of politeness and charm may make you fall in love with me before the test even begins.

Sheldon: As much as I'd love to meet Euclid, inventor of the geometric proof, he probably wore sandals and I can not look at toes during dinner.

Sheldon: I had the same feeling when I made my dad buy a betamax instead of a VHS.
Amy: You were just a little kid.
Sheldon: A little kid who picked the wrong format to record the MacNeil/Lehrer Report.

Penny: What's yours?
Sheldon: I wake up. I enjoy some french toast with butter and syrup. Then a wormhole opens and whisks me millions of years into the future, where my towering intellect is used to save the last remnants of mankind from a predatory alien race.
Penny: Interesting you didn't mention Amy.
Sheldon: Who do you think made the french toast and syrup?

Mary Cooper: Sheldon Lee Cooper, you get back in this room right now. And bring a mop!
Sheldon: Did you hear that? A mop! I've got two PHDs yet somehow I'm the janitor of my sister's birth canal.

Sheldon: Given our new found intimacy, I'd say we have some hard choices to make.
Penny: Like what?
Sheldon: Gary Con. Do we fly or drive? Do we wear costumes? And if so, who gets to be Gary?

Sheldon: We might as well stop. It's a stalemate. You're beating me at tetris, but you've got the upper body strength of a Keebler Elf.

Sheldon: Remember the old days when I would point out that your check engine light is out?
Penny: Yes.
Sheldon: Well, get ready to stroll down memory lane. Penny, your check engine light is on.

Bernadette: Hey! Sheldon, Leonard, living room right now.
Sheldon: She said my name first. That must kill you.