Penny: I should have been honest with you and told you the gift was too much.
Amy: Yes, too much. Because our friendship is fundamentally asymmetrical. I clearly like you more than you like me.
Penny: I don't think you can put a number on how much one person likes another.
Amy: I bought you a painting, that's 12 square feet in area. There's a number.
Penny: Amy, come on...
Amy: If you don't like feet, you can try dollars. The painting set me back three grand.

Penny: Okay, look, I didn't want to say this, but the real reason I took the painting down was because it made Bernadette very jealous.
Amy: Oh, my goodness, how could I have not seen that? The painting is a constant reminder that of the three of us, she is the least cool.

Amy: Oh, what a great movie.
Penny: I cannot believe you've never seen Grease.
Amy: My mother didn't allow me to watch it. She was afraid it might encourage me to join a gang.

Amy: Well, it sounds like you're saying that I could do better than Sheldon.
Bernadette: Boy, these drinks are strong. Oh mama, I'm gonna be huggin' the toilet tonight.
Amy: No, tell me, I want to know what you meant by that.
Bernadette: I just meant that you're not married and your boyfriend's kind of, Sheldon.
Amy: And your husband is extremely Howard.

Bernadette: (on the phone) Howie, stop. I can't talk like that. Amy's right here.
Amy: (on the phone) Sheldon, stop. For the last time, I will not bring home bed bugs.
Bernadette: The hotel's nice. There's a pool, a gym, the bar looks like fun.
Amy: Because I looked in the bed, and there are no bugs.
Bernadette: Aw, I love you, too. If I don't talk to you before you go to sleep, I'll meet you in dreamland.
Amy: Good night. No, I will not consider sleeping in my garment bag.

Bernadette: I was thinking of going to the lecture on posterior cingulate cortex lesions in the formation of autobiographical memory.
Amy: Oh, brain lesions are fascinating. Unless they're yours, then they're a drag. Bernadette: To the advancement of science.
Amy: And to the sick and dying who make it possible.

Penny: Please come out, Bernadette. Let's talk through this.
Bernadette: No, leave me alone.
Amy: Perhaps you should give him a taste of his own medicine. Do you have a cousin who you find attractive?
Penny: Amy!
Amy: Hey, you introduced him to the sleaze bag. I'm just trying to clean up your mess.

Bernadette: I don't know what I'm going to do. I'm supposed to marry Howard in a couple of weeks and I'm not sure I even know who the man is any more.
Amy: I'm curious what's bothering you most, the borderline incest, the prostitute or group sex with the girl dressed as the children's cartoon?
Penny: Amy, remember when we went over things that would be helpful and things that wouldn't?
Amy: Right. And that was...
Penny: Not.

Amy: All right, pivoting to the big question. Bernadette, on your wedding night you'll be consummating your marriage. What do you think your first sexual position will be as husband and wife?
Bernadette: Amy, please.
Amy: Keeping in mind that whoever's on top may set the tone for the marriage.
Penny: Okay, show's over.
Amy: Hey, they may conceive a child on their wedding night. Don't you think the kid might get a kick out of knowing how it happened?
Penny: I don't care. Ask her things like are you going to take Howard's name? Not who's going to sit on who.

Bernadette: Plus, he set up our beautiful wedding website with cute little facts about our family histories. Do you know, for a while in Poland, my family and his family were neighbors.
Penny: Oh, that's cool.
Amy: No, it's not. I'll explain it to you later.

Amy: Are we talking about women wanting penises? Because I'd like to weigh in.

Amy: So, girl talk?
Penny: Um, sure. What do you- what do you got in mind?
Amy: Do you subscribe to the Freudian theory of penis envy?
Penny: Um, I never really thought about it. Why?
Amy: Sometimes I think it might be nice to have one.
Penny: Really?
Amy: Not for sex, for convenience. You can't deny that, by comparison, our internal plumbing is extremely high maintenance.
Penny: Again, I've never given it much thought.
Amy: We have time now. Think about it.

Bernadette: Thanks. I'll sleep on the floor.
Amy: Not necessary. Penny and I are perfectly comfortable sharing a bed.
Penny: We are?
Amy: Of course, we're best friends.
Penny: Oh, right, right, the blog.
Amy: Word of warning, though. I'm prone to night terrors, so if I wake up kicking and screaming, don't panic. Just pin me down and stroke my hair, and I'll be fine.

Penny: You know, it is going to be difficult, but I'm going to cancel my plans so I can do this for my bestie.
Amy: Please don't touch my breasts.
Penny: I- I wasn't going to.
Amy: All right. I just want to establish boundaries.

Amy: Then what the hell, Sheldon? We have been going out for over two years, and I have been nothing but patient with you. I watch your dopey space movies. I signed your ridiculous contract. I even stopped wearing lip gloss 'cause you said it made my mouth look too slippery. I am the best girlfriend youre ever gonna have. You give me one good reason why I can't live here.