Leonard: Maybe I'll move in with Penny, or maybe she and I'll take this place and you can move across the hall.
Sheldon: Move across the hall?! Did you take a marijuana?

Sheldon: I see. You're putting your future bride's happiness above mine.
Leonard: Well, yeah!
Sheldon: Wow.

Leonard: Sheldon, I wasn't done talking. She hands in the paper tomorrow. I know I could help her. And she's my girlfriend. I, I should be allowed to help her. Why aren't I allowed to help her?
Sheldon: Yeah, I hear you, brother.
Leonard: No. You need to give me some advice.
Sheldon: Fine. Women, huh?
Leonard: No, specific to my situation.
Sheldon: Blond women, huh?
Leonard: Empathetic.
Sheldon: It sucks to be you.
Leonard: I quit.

Leonard: All right, you brought this on yourself. Sheldon, get him.
Sheldon: If a zombie bites you, you turn into a zombie. However, if a mummy bites you, all you turn into is some schmo with a mummy bite. So, like a zombie that's been eaten from the waist down, you, sir, have no leg to stand on.

Penny: He means he's writing a book.
Leonard: I do. It's something I've been thinking about for a long time. Yeah. It's about a brilliant physicist who solves crimes using science.
Sheldon: Oh, Leonard-
Leonard: It's not about you.
Sheldon: He probably has to say that for legal reasons.

Leonard: Okay, if I may drill down to the bedrock of my question, why did you throw it out?
Sheldon: Because I have no interest in standing in the Rose Room of the Pasadena Marriott in front of a group of judgmental strangers, who wouldn't recognize true genius if it were standing in front of them giving a speech. Which, if I were there, it would be.

Sheldon: You know, in the future, when we're disembodied brains in jars, we're going to look back on this as eight hours well wasted.
Raj: I don't want to be in a jar. I want my brain in an android body. Eight feet tall and ripped.
Howard: I'm with you. I just have to make sure if I'm a synthetic human I'd still be Jewish. I promised my mother.
Raj: I suppose you could have your android penis circumcised. But that's something your Rabbi would have to discuss with the manufacturers.
Sheldon: Not to mention you'd have to power down on Saturdays.

Leonard: I've dated plenty of women. There was Joyce Kim, Leslie Winkle.
Sheldon: Notify the editors of the Oxford English Dictionary. The word plenty has been redefined to mean two.

Leonard: Seriously? You don't even have a change of clothes or a toothbrush.
Sheldon: My plan is to stop at malls and buy what I need. It's called living off the land.

Amy: Penny gets 20 points for the sewing kit.
Sheldon: Yeah, minus five, because this is mine.

Leonard: I would appreciate it if you would, you know, make yourself scarce.
Sheldon: Leonard, I am a published theoretical physicist with two doctorates and an IQ which can't be accurately measured by normal tests, how much scarcer could I be?

Sheldon: As a Texas gentleman, I'm inclined to say ladies first. Although, I'm concerned that level of politeness and charm may make you fall in love with me before the test even begins.

Sheldon: We're scientists, we can conduct our own research. I propose that we imprison two street people-
Amy: No.
Sheldon: You didn't even let me finish.
Amy: Forget it.
Sheldon: Oh, so you can experiment on all the apes you want, but I want to manipulate the emotions of two captive human beings, suddenly I'm the monster.

Stuart: Yeah, this one made me go for ice cream and talk about her day. Spoiler alert: it was fine.
Amy: It wasn't fine. I got trapped in an elevator.
Sheldon: I may have missed a few details. The bottom of my cone was drippy.

Sheldon: As much as I'd love to meet Euclid, inventor of the geometric proof, he probably wore sandals and I can not look at toes during dinner.