Penny: I thought you were looking at a cliff on the beach.
Amy: We were, but Sheldon didn't like any of them. Some were too beachy, some were too cliffy.
Sheldon: And all of them were too outsidey.

(Leonard standing outside the door to Sheldon and Amy's apartment)
Leonard: Help! Cinnamon's loose in the building!
Sheldon: (Inside) Amy, quick, lock the door!

Sheldon: So that's all this day was? A plan to butter me up before delivering bad news?
Leonard: Come on, buddy.
Sheldon: No, I thought we were friends. You asked for a sip of my Icee. If you had your own straw, I might've said yes.

Sheldon: Hello?
Leonard: Oh, hey, where you been? We've been calling you for hours.
Sheldon: Oh, I'm sorry, my phone was on "airplane" mode.
Leonard: Why?
Sheldon: Because I was on an airplane. (makes confused gesture to Amy)

Sheldon: You know what? Let me give you a better question. Here, um, "Dr. Cooper, "I heard you were working on a top-secret project "for the U.S. military. Why don't you tell us about that?" See, that's a great question.
Dr. Harris: Okay, what was that like?
Sheldon: Oh, I can't tell you that, it's top-secret.

Amy: Okay, you ready?
Sheldon: Yeah, almost. I'm working on my facial expressions. See, uh, I've got interested. Hmm.
I've got very interested. Hmm.
Oh, and, uh, enraged.
Amy: Why would you be enraged?
Sheldon: Better to have it and not need it than to need it and not have it.

Sheldon: Very well. You may celebrate my life by throwing a party with cake, presents and a shower of admiration and love. But then you owe me big-time.

Wil Wheaton: Hello, Sheldon. I suppose you've come here to tell me that you've moved me to your super secret enemies list.
Sheldon: I don't have a super secret enemies list. I'm not a Bond villain. I'm just a regular guy, with a regular enemies list.

Sheldon: What is it?
Amy: Well, your birthday's coming up and you've never let us celebrate it. And I was hoping maybe this year we could.
Sheldon: Oh, I suppose that's a discussion we could have. (Sheldon runs back up the stairs)
Amy: Okay, great, I mean, it doesn't have to be a big party or anything. I was just - Where'd he go?

Leonard: Maybe you should consider women who aren't in serious relationships with your closest friends?
Sheldon: There's that prostate doctor, but I'm still mad at her.

Amy: What's with the blinking?
Sheldon: It's Morse code. So we can talk about without hurting --'s feelings.
Amy: Sheldon, I don't know Morse code.
Howard: I do. And if you have something to say, you can say it to my face.

Sheldon: I always looked up to you and Pop-Pop. I know what a challenging man he could be, but I saw you stand by him and make him into a better person.
Meemaw: I did.
Sheldon: Yeah, well, that is exactly what I've been doing the last five years with this little work in progress.
Leonard: He never disappoints, does he?

Meemaw: Sheldon, tell this girl that my ring will never be on her finger.
Sheldon: Yeah, I'm gonna opt out of that one, too.

Penny: Yeah, the last time I got a hand written letter, it was from someone who told me I parked like a blind person.
Leonard: That someone has a name.
Sheldon: Uh, thank you.

Sheldon: Read it back to me?
Leonard: Oh, hang on. "Yes, one might question the $20 billion "to build and run the Large Hadron Collider, but on the other hand..."
Sheldon: Okay. Um, oh, oh! "On the other hand, contrary to predictions, the collider didn't create a small black hole that devoured the Earth and life as we know it." So, money well spent.