Penny: (To Raj's dog) Bark once if you need me to call PETA.

Penny: What are you doing back?
Leonard: We got a flat and couldn't get the tire off.
Penny: Oh, I'm sorry.
Leonard: Thank you.
Penny: If it makes you feel any better, I pierced Amy's ears and her mom made her sit in my closet.
Sheldon: We blew up Feynman's van.
Penny: My dad killed my pig with his tractor.
Leonard: I spent the night in Mexico with Sheldon.
Penny: You win.

Leonard: Once you open the box it loses its value.
Penny: Yeah, yeah. My mom gave me the same lecture about my virginity. I gotta tell you, it was a lot more fun taking it out and playing with it.

Penny: Here you go, [to Leonard] quesadilla, [to Howard] salad, [to Raj] here's your pizza. And thanks to Sheldon's heated discussion with my manager, one barbecue bacon cheeseburger, barbecue sauce, bacon, and cheese on the side.
Sheldon: Thank you!
Penny: Go ahead. Eat it. I dare you!

Sheldon: I still don't see why I need a driver's license. Albert Einstein never had a driver's license.
Howard: Yeah, but Albert Einstein didn't make me wet myself at 40 miles an hour.
Penny: Yeah, and I never wanted to kick Albert Einstein in the nuts.

Sheldon: Now remember, you were given powerful pain medication and a muscle relaxer, so don't operate heavy machinery, and try not to choke on your own drool. [goes to leave]
Penny: Wait! You have to help me get into bed. [laughs] "Sheldon has to help me get into bed". Bet you thought I'd never say that!
Sheldon: Yes. Charmed. Your drug-addled candor knows no bounds. [helps Penny into bed]
Penny: You know people think you are this weird robot man who's so annoying all the time and you totally are. But then it's like that movie Wall-E at the end. You're so full of love and you can save a plant and get fat people out of their floaty chairs.
Sheldon: That's a fairly labored metaphor but I appreciate the sentiment behind it.

Penny: [to Raj] Run to India.

Penny: Give my friend his stuff back.
Tod Zarnecki: I don't know what you're talking about.
Penny: Well then good news. Today's the day a girl's finally going to touch you in your little special place. *Kicks him in the groin*

Leonard: I don't believe it. What's gotten into him?
Penny: Oh, maybe a couple of virgin Cuba Libres that turned out to be kinda slutty.
Leonard: You didn't.
Penny: Hey, you do your experiments, I do mine.

Penny: Hey, what are you guys doing here?
Howard: We're grown men, we drink at bars.
Penny: No and no. Everything okay with you and Bernadette?
Howard: Oh yeah, sure.
Penny: You and Amy? Good?
Sheldon: Oh, better than good.
Penny: You know those girls text me every detail of their lives as it happens.

Penny: Oh, I get it. Like C-3PO. ... What happened to me?

Sheldon: Amy's mad at me, and I'm not clear why.
Penny: Okay, were you talking before she got upset?
Sheldon: Yes.
Penny: That's probably it.

Penny: Come on, Amy, show us the dress.
Amy: Okay, but I'm really stepping outside of my comfort zone here.
Penny: Uh, I don't think any of your comfort zones are showing.

Penny: Wait. Wait, Sheldon come back, you forgot something.
Sheldon: What?
Penny: This plasma grenade. Ha! Look, it's raining you!

Howard: I'm not signing a prenup.
Penny: All right, Howard Wolowitz, listen up! You sign anything she puts in front of you, because you are the luckiest man alive. If you let her go, there is no way you can find anyone else. Speaking on behalf of all women, it is not going to happen, we had a meeting.