Leonard: Uh, sleep night. I mean, obviously, good night. I started to say sleep tight then I changed my mind in the middle. I swear to God, I'm smart.
Sheldon: Get it together, man.

Sheldon: (To a policeman) They took our TV, two laptops, four external hard-drives, our PS2, our PS3, our X-Box, our X-Box 360, our classic Nintendo, our Super Nintendo, our Nintendo 64 and our Wii.
Leonard: We like games.
Sheldon: Right, games. They took Halo 1, Halo 2, Halo 3, Call of Duty 1, Call of Duty 2, Call of Duty 3, Rock Band, Rock Band 2, Final Fantasy 1 thru 9, The Legend of Zelda, The Legend of Zelda: Ocarina of Time, The Legend of Zelda: Twilight Princess, Super Mario Brothers, Super Mario Galaxy, Mario and Sonic at the Winter Olympics and Ms. Pacman.
Policeman: (Writing down) Assorted video games.

Sheldon: No, I know, but plenty of things are addictive after a single exposure. I mean, crack cocaine, nicotine, Pringles. You know, once one pops one just can't stop.

Sheldon: If it's like your 3-D chess game, then you're out of your length, width and depth. Amy, get the Neosporin, somebody just got burned.

Amy: What is this?
Sheldon: A functional MRI of my brain. I did Sudoku before they took it so I'd be ripped.
Amy: I love it. Thank you.
Sheldon: And it's not just an MRI. The orbitofrontal cortex is lit up because I was thinking of you.

Sheldon: I knew we should've never mentioned us living together in the first place.
Amy: She was gonna find out eventually.
Sheldon: Disagree. We've known about evolution since 1859. She still believes in Noah and his amazing zoo boat.

Amy: What is this?
Sheldon: I'm mapping basic topics of conversation and with whom they can be discussed.
I call these circles "Zones of Privacy". Don't Google that unless you want to see pictures of people's genitals.

Sheldon: Physicist, baker, lover, what can't I do?

Sheldon: Because there's only one of me, I'm more valuable.
Penny: Right.
Sheldon: Although, Amy's already taken me out of my package and played with me.

Sheldon: Fun? Mixing Dungeons and Dragons with Christmas is like making a sandwich of grape jelly, the best-tasting jelly, and petroleum jelly, the worst-tasting jelly.

Raj: No, no, no, no! That rate is much too low for what we'd expect from this collision. Do you understand that we're talking about dark matter colliding in outer space?
Sheldon: Of course I understand. And who are you to tell me about outer space?
Raj: I'm the astrophysicist. Astro means space.
Sheldon: Astro means star.
Raj: Okay, well, let me just tell you, if we were having this argument in my native language, I'd be kicking your butt.
Sheldon: English is your native language.

Sheldon: Oh! There isn't enough chamomile tea in the world to quell the rage in my heart.

Sheldon: No, the campus isn't safe at night. There's raccoons and undergrads just walking around like they own the place.

Leonard: Sheldon, we have to do this.
Sheldon: No we don't. We have to take in nourishment, expel waste, and inhale enough oxygen to keep ourselves from dying. Everything else is optional.

Amy: So, you're just gonna sit here by yourself and do nothing?
Sheldon: Of course not. I'm going to write mean comments about Wil's show online.
Amy: Well, you can't criticize something you haven't seen.
Sheldon: I'm sorry, are you familiar with the Internet?