Sheldon: I don't think that you should demand to be in charge of a plasma project.
Leonard: Well, big surprise. You can't stand the idea of me succeeding.
Sheldon: No. I'll be honest. New assertive Leonard is going to take some getting used to. But so did cargo pants Leonard, hmm? Who, for the record, I miss. He always had gum.

Penny: Sheldon, if this is what he wants, he should ask for it. I mean, what's the worst that happens? They say no.
Leonard: Well, I'm not gonna let them say no. If they don't want me to quit, this is what it's gonna take.
Penny: Wait, you're gonna quit?
Leonard: Yeah. It's like you said, I have to go after what I want, and if I can't get that at Caltech, there are plenty of other universities in the world.
Penny: W- In the world? I can't even get you to go to the beach, and now you want to move to the world?

Leonard: [to Penny] Fine, you want to talk about it? Let's talk about it. I-I'm not loving my job right now. And this is something that would make me happy. Don't you want me to be happy
Sheldon: [to Penny] Oh, I've been dinged on this before. Whatever you really think, you have to say yes.
Penny: [to Leonard] Of course I want you to be happy.
Sheldon: [to Penny] Well played.

Leonard: So, I spent the whole day putting together this proposal, and tomorrow I'm gonna tell President Siebert that this is what I want to do.
Penny: Oh. Well, this looks great.
Leonard: You didn't even open it.
Penny: Well, no, it's got a nice, you know, science-y heft to it.

President Siebert: No.
Leonard: I'm sorry, President Siebert, but I'm not taking no for an answer.
President Siebert: I speak a little Russian. Will you take nyet for an answer?
Leonard: I'm serious.
President Siebert: Oh. Well, that changes everything.
Leonard: Really?
President Siebert: Nyet.

Raj: Now I'm some sort of big joke. I'm even on some alien conspiracy blog. See? "Caltech astrophysicist finds proof of alien life''
Howard: Wow, that is not a great picture of you.

Sheldon: Leonard's about to demand a job that I don't think the university will give him. I'm worried he's making a giant mistake. But maybe I only think that because deep down I don't want him to succeed.
Amy: The fact that you're worried about your motivation supports the idea that you genuinely care for your friend.
Sheldon: I do. Thank you, Amy. You know what? After I've talked to Leonard, you've earned yourself a bonus lecture on Sponge Hulk.
Amy: That'll show me.

Amy: Wow. Déjà vu.
Sheldon: Amy, you're a neuroscientist. you know the latest research into déjà vu suggests it's nothing but the frontal regions of the brain attempting to correct an inaccurate memory.
Amy: You telling me stuff I already know is definitely déjà vu.

Sheldon: How can I tell if I'm doing something for a noble reason or a selfish reason?
Amy: Try saying the thing in your head and see if you can add the words, "That'll show 'em."

Leonard: Always wanted to be the principal investigator on a plasma physics study.
Sheldon: Hey, look at that. The new you's funny, too.
Leonard: I'm serious. You know I'm gonna put together a proposal and tell President Siebert this is what I want to do. If he doesn't let me, there's plenty of other universities that will.
Sheldon: Sure there are. [winks]

Sheldon: Leonard, where are you going?
Leonard: Well, to work. Just trying out a different route.
Sheldon: Okay. If we cross the county line, it's technically kidnapping.

Leonard: Well, if you don't approve of my driving, too bad. This is the new me. Get used to it.
Sheldon: Fine. Then this is the new me, and he finds the new you tiresome.
Leonard: How is that different than the old you?
Sheldon: The new me gives knowing winks. [winks]

Leonard: Well, all these years, I-I was afraid to say what I wanted. You know, even at work, you know, there's things I want to accomplish, but I didn't want to ruffle any feathers or step on any toes.
Sheldon: Feathers and toes? Is the new thing you're trying to accomplish ballroom dancing with a chicken? Look at that. The new me is hilarious.

Amy: It's fine. We'll have barbecue.
Sheldon: Oh, of course. I'm nothing if not flexible. I'm sure that at some point in the 3,000-year history of the Chinese empire, a cavalryman crossing the Gobi Desert was forced by hunger to eat his own horse and roast it over a campfire, hence, Chinese barbecue.

Sheldon: Gee, I'm sorry, I didn't watch the news today. Has the whole world gone mad?
Leonard: It's my house. I'm tired of being told where I can and can't sit.
Sheldon: [to Penny] You did this. Amy, grab your meat. We're leaving in a huff.
Amy: I'm sorry, if I don't go now, it's not a huff.