Penny: Look, I know this is your wedding, and you can do whatever you want, but if you think anyone but me is gonna be your maid of honor, then you're an idiot because you are my best friend.
Howard: Too late, Bernade-
Amy: (pushes Howard out of the way, rushes to hug Penny) Bestie!

Amy: So are you feeling okay? No wedding jitters?
Sheldon: No. There is nothing in the world that would stop me from marrying you tomorrow, even me from the future coming back to prevent the wedding and the subsequent birth of a child who will destroy humanity.
Amy: Because if you came from the future, that would mean you already went through with the wedding because you believe that time travel is on a closed loop.
Sheldon: I love you so damn much.

Leonard: Oh, hi, you wanted to see me?
Ms. Davis: Yes. I wanted to talk to you about the e-mail you sent me last night.
Leonard: I sent you an e-mail?
Ms. Davis: You bet you did. "Hello. Shalom and aloha from the grave of Richard Feynman."
Leonard: (groans) Oh, it's coming back to me.
Ms. Davis: "Please accept the following retraction: I know I said physics is dead, but it is the opposite of dead. If anything, it is undead, like a zombie. Speaking of which, if Richard Feynman came back as a zombie, I would totally let him bite me."
Leonard: Any chance that's the end?
Ms. Davis: "I got bit by a squirrel once. I had to get rabies shots. I cried so much, my mother said 'don't be a baby'. In conclusion, physics is great. Squirrels suck, and someday, I'm gonna put my mom in a cheap nursing home. Yours truly, XOXO, Dr. Leonard Hofstadter."
Leonard: I-I-I can explain.
Ms. Davis: "P.S Can you come pick us up? The Uber driver won't open the door because Sheldon is covered in blue vomit."

Bernadette: One of the great things about being pregnant is drinking cranberry juice out of a wineglass and watching people freak out.

Sheldon: Wow! You look beautiful.
Amy: Really? 'Cause I was gonna return it.
Sheldon: Why would you return it? You look like a pile of swans.

Sheldon: They're very different. Physics answers the question: what is the nature of the universe? Geology answers the question: you know, what'd I just trip over?

Sheldon: Can I get you anything else?
Amy: No, thanks. I think I'm good.
Sheldon: You sure? There's still plenty of pork fat. Although, if we don't eat it, I suppose we could turn it into soap.
Amy: That might taste better.

Howard: Bernie, this is our kid's name. I think we should both agree.
Bernadette: You're right. We both made this baby.
Howard: Thank you.
Bernadette: And I carried it, had to stay in bed for four months, sacrificed my body and my job, and soon it's gonna burst its way out of me like the Kool-Aid Man.
Howard: Exactly. Fifty-fifty.

Bernadette: At the office, I have two assistants! I don't even know their names. I just call them Thing 1 and Thing 2.
Amy: I don't have assistants.
Bernadette: I guess that's one of the benefits of being in the private sector. That and all the money I make!

Barry Kripke: At wast, my wove has come awong, my wonewy days are over, and wife is wike a song, oh, yeah.

Amy: So, you're just gonna sit here by yourself and do nothing?
Sheldon: Of course not. I'm going to write mean comments about Wil's show online.
Amy: Well, you can't criticize something you haven't seen.
Sheldon: I'm sorry, are you familiar with the Internet?

Sheldon: Oh, Stuart, good. I was wondering, will you be accepting Bitcoin?
Stuart: Well, I don't know what that is, but it's got "coin" in it, and my cash register doesn't, so yeah.

Sheldon: Amy, I usually know exactly what to say. But in this moment I have no words.
I guess I'm overwhelmed by you. In a good way. Not in the elevator in the Haunted Mansion way. Even if I can't tell you now how I feel, I will spend my life showing you how much I love you.

Sheldon: Uh-oh.
Amy: What?
Sheldon: I left the food out.
Amy: You afraid it's gonna go good?

Howard: (singing) Alone in my temple in the middle of Peru, A giant stone ball with nothing to do,
Raj: But if you steal my idol, I will roll right over you
All: Cause I'm six tons of granite, And micaceous schist. Yeah, I'm six tons of granite, And micaceous schist,
Bert: I'm gonna crush you, I'm gonna mush you, You took my idol, I'm homicidal, Gonna roll over you till your brains come out, And your bones will crunch and your blood will spout! I'm not just a rock, baby. I'm a boulder.
All: Cause I'm six tons of granite, And micaceous schist. Yeah, I'm six tons of granite, And micaceous schist, Yeah, I'm six tons of granite-