Leonard: If I take it off, Sheldon wins.
Penny: Sweetie, every night you don't kill him in his sleep, he wins.

Sheldon: I know why. You've come to me because you're my Obi-Wan.
Arthur: I'm not familiar with that. Is that an Internet?

Howard: So you can never take it (the sweater) off?
Leonard: No.
Raj: Not even to sleep?
Leonard: No.
Howard: So you're just an idiot?
Leonard: It's called proving a point.
Howard: Is the point you're an idiot?

Raj: [to Amy] If you were having Sheldon's baby, would you really want him in the room?
Penny: Yeah, if he's in the room when they're making the baby, I'll give you $10.

Amy: Do you have any idea how hard it is to laugh at a knock knock joke that starts "Knock Knock Knock, Amy. Knock Knock Knock, Amy. Knock Knock Knock, Amy"?

Sheldon: Sheldon Cooper does not get lucky.
Amy: You and me both, brother.

Amy: I guess it must have been back when I was in the Girl Sprouts.
Bernadette: Girl Sprouts?
Amy: My mom made it up as an alternative to the Girl Scouts. She didn't want me selling cookies on some street corner like a whore.

Bernadette: Maybe we should get one of those machines to help her up the stairs.
Howard: You mean a fork lift?

Bernadette: (Shouting from the bathroom) How many times do I have to tell you to replace the toilet paper when it's empty?
Howard: I'm in the middle of something.
Bernadette: So am I!

Penny: Sheldon, what did we say about being a nicer friend?
Leonard: Thank you.
Penny: Leonard, what did we say about being a gullible weeny?

Sheldon: Sheldon Cooper does not cry.
Howard: That's true, you'd rust.

Bernadette: Aww, Raj did the dishes.
Howard: How do you know I didn't do them?
Bernadette: Because once when all the knives were dirty, you cut a bagel with your keys.

Penny: Howard, cow tipping - real or not?
Howard: I'm going to say not. That's just based on me trying to roll my mom over when she's snoring.

Leonard: You don't go into science for the money.
Bernadette: Speak for yourself. Last month my company both invented and cured restless eye syndrome. Ka-ching, ya blinky chumps!

Sheldon: Well, this is confusing for me. But I don't want to stand in the way of your happiness. So, I will condemn you internally while maintaining an outward appearance of acceptance.
Mary: That is very Christian of you.