Penny: Do you even like the Beach Boys?
Sheldon: They have "beach" right in the name. What do you think?

Raj: And you know we get to name it.
Sheldon: We better choose a name no one can make fun of. Sir Frederick William Herschel didn't do Uranus any favors.

Meemaw: Sheldon, tell this girl that my ring will never be on her finger.
Sheldon: Yeah, I'm gonna opt out of that one, too.

Sheldon: I always looked up to you and Pop-Pop. I know what a challenging man he could be, but I saw you stand by him and make him into a better person.
Meemaw: I did.
Sheldon: Yeah, well, that is exactly what I've been doing the last five years with this little work in progress.
Leonard: He never disappoints, does he?

Sheldon: What is it?
Amy: Well, your birthday's coming up and you've never let us celebrate it. And I was hoping maybe this year we could.
Sheldon: Oh, I suppose that's a discussion we could have. (Sheldon runs back up the stairs)
Amy: Okay, great, I mean, it doesn't have to be a big party or anything. I was just - Where'd he go?

Sheldon: Very well. You may celebrate my life by throwing a party with cake, presents and a shower of admiration and love. But then you owe me big-time.

Sheldon: So, did you defile my mother or not?

Amy: Well, for starters, there's nothing wrong with keeping our toothbrushes in the same holder.
Penny: Sheldon, what do you say to that?
Sheldon: I think we should see other people.

Leonard: Now we're going as Hulk and She-Hulk. I don't want to take my shirt off at Comic-Con.
Sheldon: If I may speak for Comic-Con, we don't want that either.

(Leonard standing outside the door to Sheldon and Amy's apartment)
Leonard: Help! Cinnamon's loose in the building!
Sheldon: (Inside) Amy, quick, lock the door!

Sheldon: Stephen Hawking is a genius. If he said 'no,' I wasn't going to waste time on her father.

Amy: I thought we agreed on June 15.
Sheldon: That's the day after Flag Day. Everyone'll be partied out.

Bert: Hey, Sheldon.
Sheldon: I've been thinking about it, and I suppose I could help you with your research.
Bert: What changed your mind?
Sheldon: Bert, I'm a gift horse. Don't look me in the mouth.

Amy: Okay, you ready?
Sheldon: Yeah, almost. I'm working on my facial expressions. See, uh, I've got interested. Hmm.
I've got very interested. Hmm.
Oh, and, uh, enraged.
Amy: Why would you be enraged?
Sheldon: Better to have it and not need it than to need it and not have it.

Penny: You should just talk to him, I'm sure you guys can work this out.
Sheldon: It's certainly preferable to my plan.
Penny: Which was?
Sheldon: A powerful laxative.