Tour Guide: And here we have the former hotel where Tesla perfected the three-phase alternating current motor.
Sheldon: That's wrong. I'm gonna say something.
Amy: Don't.
Sheldon: Well, then how will everyone know I'm the smartest boy here?

Amy: Just let it go.
Sheldon: Is everything all right? You seem testy this morning.
Amy: I'm not testy.
Sheldon: I'll have to take your word for it. There's no test for testy.

Sheldon: Is it possible that you're sexually frustrated?
Amy: Okay, now I'm testy.
Sheldon: If you had adhered to my coital schedule, your brain would be floating on a sea of oxytocin right now.
Amy: Don't talk to me about my brain. I'm a neurobiologist.
Sheldon: Then you should know the benefits of the special hug that grown-ups give each other.
Amy: Sheldon, everybody's listening.
Sheldon: Of course they're listening; we're interesting.

Sheldon: I'm only recently married. Do I stay here? Do I follow? Say something useful.

Leonard: Morning, sunshine. So I see you're making espresso.
Penny: Yup. Just need that extra jolt for a successful day of ballbusting.

Penny: You know, you compared us to the strangest couple we know, and we know Amy and Sheldon, Howard and Bernadette, Raj and his twitchy little dog.

Leonard: Mrs. Fowler is an angry, vindictive woman, whereas you are warm and-and loving, quick to forgive.
Penny: Oh, please.
Leonard: I'm serious. And I'm nothing like Amy's dad. He's a mousy little man who can't stand up for himself.
*Penny stares at Leonard*
Leonard: My point is you're not like her, so we're not like them.

Penny: Well, 30 years from now, are you gonna hide from me because I'm so scary?
Leonard: Hey, I don't think you're scary. Yes, I flinch when you make sudden moves, but that says more about my childhood than you.
Penny: Aw.
*Penny goes to huge Leonard, he flinches and backs away. He recovers and hugs her.*

Raj: Hang on, I'm checking to see if Neil replied to my latest smackdown.
Bernadette: Really? Don't you think this Twitter feud is a little silly?
Raj: Absolutely not. It's two respected scientists debating opposing views in a public forum.
Howard: You called him Mike Tyson's little sister.
Raj: Yeah, and now Mike Tyson's mad at me, too.

Mrs. Fowler: He said he needs a break, and I'm too much for him.
Penny: Oh. I'm sure he didn't mean that.
Mrs. Fowler: He said I'm overbearing!
Penny: Oh, please, you're just the right amount of bearing. Look, I know he loves you. If you just give him some space, I'm sure he'll come back.
Mrs. Fowler: You really think so?
Penny: Yeah, I do.
Mrs. Fowler: You're a good person, Penny. I hope we get to spend lots of time together.
Penny: Me, too.

Penny: Hit the road.
Mr. Fowler: But-
Penny: Now!
Mr. Fowler: Can I get my stuff?
Penny: Be quick about it!

Sheldon: I brought you two hot dogs.
Amy: Aren't you gonna eat one?
Sheldon: From a street cart? Are you crazy? I'm amazed that I'm holding them.

Sheldon: You realize that I'm not a particularly physical person.
Amy: I know.
Sheldon: When I was little, and people asked me what I wanted to be when I grew up, I'd always say, "A brain in a jar."
Amy: Sure.

Sheldon: I'm just worried that if I don't schedule our bedroom endeavors, then I may not think about them, and you'll grow cold and distant and seek solace in the arms of a heavily-muscled longshoreman.
Amy: Where would I find a longshoreman?
Sheldon: Along the shore. It's in the name.

Amy: Sheldon, I could never be with anybody but you.
Sheldon: That's good to know. I wouldn't want to fight a man who's brave enough to touch a fish.