Leonard: It must be hell inside your head.
Sheldon: At times.

Sheldon: I'll walk you through it. This game is not called Words with Strangers. No, it's not even called Words with Acquaintances. It's called Words with-
Raj: I'm not finishing your sentence. You pulled the plug on my funk.
Sheldon: Friends! It's Words with Friends. Which Stephen Hawking and I officially are. Now all I need is a bunk bed with a slide, and I'll have everything I've ever wanted since I was six years old.

Howard: This is a twist. Usually you're the one getting called into H.R.
Raj: Yeah, now it's Amy. Who knew you were married to such a bad girl.
Sheldon: I suppose the signs were always there. I mean, she did recently go to that rave at the mall.
Amy: It was a Spencer's Gifts.
Sheldon: There was music and a strobe light. If that isn't a rave, then I don't know what one is.
Leonard: You don't know what one is.

Amy: Hi.
Sheldon: Hello.
Amy: Huh. Looks like you've been busy.
Sheldon: Oh, I have. Uh, dark matter, uh, reconciling gravity and quantum mechanics. Supersymmetry. I've figured out the biggest problems in physics today.
Amy: Wow, you solved them all?
Sheldon: No, I just, I figured out that they're the biggest problems.

Leonard: I grew up in a house full of crazy academics. Instead of leaving Santa milk and cookies, we had to leave him a research paper. And in the morning, you could tell he'd been there because the paper would be graded.
Sheldon: No wonder you love Christmas. That sounds amazing.
Leonard: It wasn't amazing. I got a C- four years in a row.
Sheldon: Yeah, I'm familiar with your work. C-minus was your gift.

Sheldon: My point is, I don't like when things change. So, regardless of your feelings, I would like you to continue dating Leonard. And also, while we're on the subject, you recently changed your shampoo. I'm not comfortable with the new scent. Please stop this madness and go back to green apple.

Leonard: This is depressing. Do you have any alcohol around here?
Sheldon: Uh, not surprisingly, when Penny moved out, she took every last drop.

Sheldon: Tell him Dr. Cooper feels that the best use of his time is to employ his rare and precious mental faculties to tear the mask off nature and stare at the face of God.
Penny: Sheldon, it's Saturday night. You'll be doing laundry.
Sheldon: Don't tell him that. Tell him the mask thing.

Sheldon: I got you a little something to help you relax.
Amy: Sheldon, that is the sweetest, most- What what is this?
Sheldon: The notes from our quantum cognition project. I thought we could spend the evening grinding away on it.
Amy: (sighs) I just got home, I'm tired.
Sheldon: Of Howard, I know. So how about you and me make some beautiful science together?
Amy: Sheldon, I want to work on this with you, just not tonight. What if we get up early and do it in the morning? I promise, I'll be way more into it.
Sheldon: You know what? There was a time that you would've been happy to stay up and collaborate all night with me. And then wake up in the morning and do it some more.
Amy: (sighs) Fine, but can we make it quick?
Sheldon: No. If you're just gonna make me do all the work, then go to bed. But don't be surprised if you walk out here and catch me doing it myself.

Sheldon: Ah, Beverly, there you are.
Beverly Hofstadter: Sheldon, how nice to see you. Leonard was just showing me his new lab.
Sheldon: Oh, yes, experimental physics, the carpentry of the science world.

Sheldon: She's going to be home at "eight-ish." Like, when is that? 8:01? 8:02? And what kind of scientist uses "-ish"?

Sheldon: My expenses account for 46.9% of my after-tax income. The rest is divvied up between a small savings account, this deceptive container of peanut brittle, and the hollowed-out buttocks of a superhero action figure who shall remain nameless for his own protection. Or her own protection.

Leonard: Oh, who am I kidding? I can't go through with this, you need to call her and cancel.
Sheldon: Me?
Leonard: Yes.
Sheldon: What should I tell her?
Leonard: I don't know. Tell her I'm sick.
Sheldon: Okay.
Leonard: Not the kind of illness that will make her want to come over and take care of me, but nothing so critical that she'll feel uncomfortable going out with me in the future if I want to try this again.
Sheldon: Got it. So I'm assuming nothing venereal. I'll just tell her that you had a routine colonoscopy and haven't quite bounced back.

Sheldon: I've been dreaming about going to the Large Hadron Collider since I was nine years old.
Leonard: Yeah, well, I've been dreaming about spending Valentine's Day with a girl since I was six.
Sheldon: Shame on you! That's no dream for a scientist.

Raj: Are there any chopsticks?
Sheldon: You don't need chopsticks, this is Thai food.
Leonard: Here we go.
Sheldon: Thailand has had the fork since the latter half of the nineteenth century. Interestingly they don't actually put the fork in their mouth, they use it to put the food on a spoon which then goes into their mouth.
Leonard: Ask him for a napkin, I dare you.