Howard: This guy knew how to live. He taught himself musical instruments. He studied Portuguese just to give a speech in Brazil.
Raj: The only part of me that's been to Brazil is my bikini line.
Penny: (taking the Romulan ale away from Raj) Okay.

Sheldon: You know, Feynman used to say he didn't do physics for the glory or the awards, but just for the fun of it.
Leonard: He was right. Physics is only dead when we stop being excited about it.
Raj: Even beyond the grave, he's imparting wisdom.
Sheldon: Um, I'm the one who remembered it.

Howard: Give me the bottle. I mean, it might be a little corny, but I say we pour one out for all the science homies who came before us.

Raj: Boo-hoo. You know what you sound like? Babies. Two whiny babies. And there's nothing worse than being stuck with two whiny babies!
Howard: Oh. Oh, my God, I'm gonna have two babies.
Raj: No, no, no, no. Babies are great. You're lucky to have two babies. I mean, look at me, uh, I'm all alone.
I'm never gonna have babies, 'cause you can't make a baby watching Netflix with your dog.
Penny: Thanks for coming.

Sheldon: It's fine. I don't need to be a theoretical physicist. There's lots of things I could use this brain for. I could be an accountant for the mob. I could guess people's weight at the fair.

Penny: That is enough. Your lives are not wasted. Your careers are not at a dead end. You just hit a rough patch. Instead of feeling sorry for yourselves, you need to get up and get inspired.
Leonard: How?
Penny: I don't know. You know, when I'm feeling down, I go for a run, which is exactly why I'm not 180 pounds, genius!

Howard: I know where we need to go.
Leonard: Are we running there? Because watching drunk Sheldon run would be the highlight of my life.

Penny: I had no idea Richard Feynman was dead.
Howard: Yep. Most people don't know he's actually buried right here in Altadena.
Sheldon: I'm sure they keep a lid on that to avoid traffic jams.

Penny: So you guys are upset because the collider thing disproved your theories?
Leonard: It's worse than that. It hasn't found anything in years, so we don't know if we're right, we don't know if we're wrong. We don't know where to go next.
Sheldon: All I know is it looks like I tongue-kissed Avatar.

Penny: Come on. You guys are physicists. Okay? You're always gonna be physicists. And sure, sometimes, the physics is hard, but isn't that what makes it boring?

Howard: We're here. What's going on?
Penny: Okay. As far as I can see, science is dead, 'cause Leonard killed it. And, uh, I don't know who the Romulans are, but those guys know how to party.

Raj: So, what do you want us to do?
Penny: I don't know. You're scientists; cheer them up.
Howard: "Cheer them up"? Do you even know what a scientist is?

Leonard: No, we don't need to be cheered up. It just turns out that physics is exactly like Lost. Started out great, and turns out just a big old waste of time.

Leonard: This is depressing. Do you have any alcohol around here?
Sheldon: Uh, not surprisingly, when Penny moved out, she took every last drop.

Sheldon: Oh, but I do have several bottles of Romulan ale that I bought at Comic-Con.
Leonard: Isn't that just vodka with blue dye in it?
Sheldon: First, physics, now Romulan ale. What else would you like to defecate on?