Bernadette: You know, you're a successful woman. You should be able to brag about your accomplishments once in a while.
Amy: Well, so should you. I mean, the guys are never shy about bragging.
Bernadette: Tell me about it. Howie texts me every time his dog levels up in Warcraft.

Amy: I guess we can brag to each other.
Bernadette: That's a great idea.
Amy: Damn right it is; I came up with it. (chuckles) That felt good.

Penny: So you guys are upset because the collider thing disproved your theories?
Leonard: It's worse than that. It hasn't found anything in years, so we don't know if we're right, we don't know if we're wrong. We don't know where to go next.
Sheldon: All I know is it looks like I tongue-kissed Avatar.

Penny: Come on. You guys are physicists. Okay? You're always gonna be physicists. And sure, sometimes, the physics is hard, but isn't that what makes it boring?

Howard: We're here. What's going on?
Penny: Okay. As far as I can see, science is dead, 'cause Leonard killed it. And, uh, I don't know who the Romulans are, but those guys know how to party.

Raj: So, what do you want us to do?
Penny: I don't know. You're scientists; cheer them up.
Howard: "Cheer them up"? Do you even know what a scientist is?

Leonard: No, we don't need to be cheered up. It just turns out that physics is exactly like Lost. Started out great, and turns out just a big old waste of time.

Raj: Boo-hoo. You know what you sound like? Babies. Two whiny babies. And there's nothing worse than being stuck with two whiny babies!
Howard: Oh. Oh, my God, I'm gonna have two babies.
Raj: No, no, no, no. Babies are great. You're lucky to have two babies. I mean, look at me, uh, I'm all alone.
I'm never gonna have babies, 'cause you can't make a baby watching Netflix with your dog.
Penny: Thanks for coming.

Sheldon: It's fine. I don't need to be a theoretical physicist. There's lots of things I could use this brain for. I could be an accountant for the mob. I could guess people's weight at the fair.

Penny: That is enough. Your lives are not wasted. Your careers are not at a dead end. You just hit a rough patch. Instead of feeling sorry for yourselves, you need to get up and get inspired.
Leonard: How?
Penny: I don't know. You know, when I'm feeling down, I go for a run, which is exactly why I'm not 180 pounds, genius!

Howard: I know where we need to go.
Leonard: Are we running there? Because watching drunk Sheldon run would be the highlight of my life.

Penny: I had no idea Richard Feynman was dead.
Howard: Yep. Most people don't know he's actually buried right here in Altadena.
Sheldon: I'm sure they keep a lid on that to avoid traffic jams.

Penny: Oh, wow. He's buried with his wife.
Raj: We get it. A lady loved you. Quit bragging.

Leonard: Feynman was so cool. When I was a kid, I'd put on some headphones and crank up one of his lectures and just jam out to knowledge.

Howard: This guy knew how to live. He taught himself musical instruments. He studied Portuguese just to give a speech in Brazil.
Raj: The only part of me that's been to Brazil is my bikini line.
Penny: (taking the Romulan ale away from Raj) Okay.