Penny: Oh, I love San Francisco. I wish I was going with you.
Sheldon: I understand your envy. This is a can't miss symposium. There are going to be discussions on bio-organic cellular computer devices, the advancements in multi-threaded task completion, plus a round table on the non-equilibrium Green's function approach to the photoionization process in atoms.
Penny: When I go, I usually just get hammered and ride the cable cars.

Sheldon: That's over the wheelbase. Are you completely unfamiliar with the suspension characteristics of a pre-1980 Pullman-built Superliner Deluxe passenger coach?
Leonard: Sheldon, we've been on this train 90 seconds, and you've already said a thousand words. Just tell us where to sit and shut up.

Leonard: Hey, Penny. It's Leonard.
Penny: Hey, Leonard. How's the train ride?
Leonard: Delightful. Listen, I don't know what you're doing right now, but there are little bubbles forming on the corners of Sheldon's mouth.

Leonard: He's calling to ask you a favor. You might be confused because he didn't use the words, Penny, Sheldon, please or favor.

Leonard: Excuse me, but what about me? Why don't I get a shot?
Howard: Fine, go ahead. Take a shot.
Leonard: You know, I've already got a gorgeous blond back home that I can't score with. I think I'll let you two take this one.

Leonard: We had a vote. Three of us voted for airplane. Sheldon voted for train, so we're taking the train.
Sheldon: Don't say it like that, Leonard. Say it like, "We're taking the train!"

Penny: The theater is above a bowling alley, so it's a little noisy, but it might be the only chance I'll ever get to play Anne Frank. And the director is brilliant. He uses the bowling sounds as, like, Nazi artillery.

Sheldon: Yes, I'm still here. Where am I going? I'm on a train. Now, what you'll be looking for is a small wooden box located between a Hoberman's sphere and a sample of quartz flecked with pyrite. Hoberman's Sphere. It's a collapsible icosidodecahedron. No, the thing with the time on it is my alarm clock.

Leonard: So you'll send him an e-mail when we get back.
Sheldon: Then I won't get to see his face light up as he reads it.

Leonard: So aren't you going to go talk to her?
Howard: I will, I'm just working on my opening line.
Leonard: She's probably heard every possible line, Howard. Why don't you just try hello?
Howard: No, no, no, that always creeps girls out. I need to come up with something thats funny, smart and delicately suggests that my sexual endowment is disproportionate to my physical stature.
Leonard: You're going to need more than 11 hours.

Sheldon: Here. I'm hoping once you reap the endorphic rewards of the steady clickety-clack of steel wheels on polished rails, your sour disposition will abate.
Leonard: Yeah, maybe. Meanwhile back in the 21st century, people are raising their tray tables and putting their seat-backs in an upright position 'cause it's time to land in San Francisco.

Howard: And did you know the word "pumpernickel" comes from the German words pumper and nickel, which loosely translates to fart goblin?

Raj: It's hot in here. It must be Summer.
Summer Glau: That's cute.
Raj: Really? I just made it up. Have you seen Slumdog Millionaire?
Summer Glau: Oh, yeah, I loved it.
Raj: It's loosely based on my life.

Leonard: Wow, teasing the guys at the Apple Store seems a little redundant now.
Sheldon: I don't follow.
Leonard: I wouldn't expect you to.

Howard: Hi, I'm the small package good things come in.