Sheldon: For what it's worth, my mother says that when we deceive for personal gain, we make Jesus cry.

Howard: Is that supposed to be funny?
Sheldon: I believe it is. The combination of the Star Trek reference and the play on words involving the double-meaning of the verb to go suggests that Leonard is humorously mocking your efforts in space plumbing.

Sheldon: Why does Leonard get to go?
Wolowitz: Because he's upset over his situation with Penny, and if I have to hear about it again, I'm gonna kick him in his ovaries!
Leonard: Thanks for understanding.
Howard: I've got your back, sister!

Sheldon: Have you notified NASA?
Howard: No. Are you crazy? What am I gonna say? I screwed up your toilet and pretty soon there's gonna be crap floating all over your nice shiny space station?

Leonard: Hey, Stuart, I need to talk to you.
Stuart: Sure, what's up?
Leonard: I think I gave you bad advice about Penny, and I want to apologize.
Stuart: No, your advice was great.
Leonard: It was?
Stuart: Yeah, going slow really worked.
Leonard: You're kidding. Never worked for me.

Stuart: Yeah, last night at dinner, I did what you told me, I went really slow, I kept my distance, and two bottles of wine later, we were making out in my car.
Leonard: Wine? I didn't say to give her wine.
Stuart: It doesn't matter, that's where it all went to hell.
Leonard: During the kissing? What did you do, sneeze in her mouth? I did that to a girl once.
Stuart: No, everything was good and really hot, and I said “Oh, Penny,” and right where she was supposed to say, “Oh, Stuart,” she said ... your name.
Leonard: Leonard?
Stuart: That is your name, right?
Leonard: Yeah, no, yeah, wow, I'm sorry. That must've been the last thing you wanted to hear.
Stuart: Well, it beats "You know I'm a dude, right?" Yeah, it was pretty bad.

Leonard: Hey Stuart.
Stuart: You busy?
Leonard: Um…
Howard: Classified, Leonard.
Leonard: Yeah, it's a regular Manhattan Project.

Sheldon: Smell that? That's the smell of new comic books. Oh, yes!
Howard: They're on me today, boys.
Raj: You're paying? Have you been selling your sperm again?

Sheldon: All right, what if we use this two-inch PVC to reinforce the center cross-support?
Howard: No good. I mean, it might work for the Japanese and the Americans, but have you seen the size of the Russians they've got up there? The thing has to hold up against a hearty potato-based diet.

Howard: Here's an approximation of the spare parts available on the Space Station. We gotta find a way, using nothing but this, to reinforce this so the waste material avoids the spinning turbine.
Raj: You mean so it doesn't hit the fan?

Howard: Ok, now, this is an exact duplicate of The Wolowitz Solid Waste Disposal System, as deployed on the International Space Station.
Raj: Don't you mean the Wolowitz Solid Waste Distribution System?

Leonard: Well, what are you gonna do?
Howard: I'm gonna figure out how to fix it, then I'll tell them.
Leonard: So, what do you need us for?
Raj: He can't figure out how to fix it.
Howard: Hey, you said you were gonna be supportive.
Raj: I'm trying, but you have to admit this is pretty damn funny.
Sheldon: I agree. It's the juxtaposition of the high-tech nature of space exploration against the banality of a malfunctioning toilet that provides the comic fodder here. Check your messages.

Sheldon: Yeah, I have to say I thought the toilet humor would get less funny with repetition. Apparently there is no law of diminishing comedic returns with space poop.

Sheldon: Hey, Stuart, have you read the new Flash?
Stuart: No.
Sheldon: Well I have and it will knock your socks off. Good luck getting them back on.

Raj: Howard, wait. Why don't you use this instead of the PVC to keep the transverse filter assembly in place?
Howard: Because this is not a spare part from the space station. This is the thing from the pizza box that keeps the lid from touching the cheese.
Raj: That what that's for? In India, the lid just touches the cheese. Of course, we also have rampant poverty and periodic outbreaks of cholera, so a little cardboard in our cheese is no biggie.