Sheldon: "Gerry the Gerbil and the bully boys on the bus." Read it, not helpful.

Sheldon: You know, I do recall seeing some female undergarments. Where was that? Oh, yes. Earlier this evening, I happened to gaze out the window and a brassiere caught my eye. Do those look familiar?

Sheldon: Doesn't anyone wanna know where he's going?
Penny: Okay, where is he going?
Sheldon: Leonard is going to the office.

Sheldon: Of the handful of women Leonard's been involved with, she's the only one I have ever found tolerable.
Penny: Well, what about me?
Sheldon: The statement stands for itself.

Penny: I'll tell you what happened. (sigh) We were young. We were very much in love, but we could only communicate through a time-travelling mailbox at my lake house.
Sheldon: It's not enough that you made me watch that movie, but now you mock me with it?

Leonard: You hacked my Facebook account?
Sheldon: Oh, it's hardly hacking when you use the same password for everything, Kal-El.

Penny: I was in junior rodeo. I can hog-tie and castrate him in 60 seconds.

Penny: Where are my clothes?
Sheldon: Your clothes?
Penny: Yes. I left them in the washers and when I went down to get them, they were gone.
Sheldon: Really? Despite the sign that says: "Do not leave laundry unattended?"

Howard: You know, the Pishkin-Wolowitz liquid-waste-disposal system is turning a few heads as well.
Ramona: Again, ew.

Leonard: Sheldon, we both agreed to do this.
Sheldon: It's a waste of time. I might as well explain thermodynamics to a bunch of Labradoodles.
Leonard: If you don't do this, I won't take you to the comic book store.

Leonard: That's it, no more Thai food.

Howard: May I say Penny, not a lot of women could look as hot as you do with such greasy hair.

Penny: Look, I said I wanted to hurt him, but this?
Leonard: It will shorten the war by five years and save millions of lives.

Sheldon: (On computer screen) Hello, puny insects, as a consequence of your efforts to circumvent my will, everyone is awarded one additional strike.
Leonard: Thanks a lot, Howard.
Howard: What are you complaining about? I'm the one who has to take the class again.

Penny: I like hanging out with you guys, but I'm not gonna apologize for something I didn't do.
Leonard: Well, actually, technically, you did do it.
Penny: That's strike one, Leonard.