Leonard: So wait,you're just gonna give up?
Sheldon: No, I'm not giving up. I never give up.
Leonard: So what is it you're doing?
Sheldon: I'm transcending the situation. I'm clearly too evolved for driving.

Sheldon: Well, those are indicators that I'm farther along the evolutionary scale than the average human.
Leonard: No kidding.
Sheldon: Well, no, no, I'm not going to go so far as to say that I represent a distinct new stage in humankind. You know, a Homo Novus, if you will. No, that's for anthropologists to decide. But I am convinced that the reason I cannot master the plebeian task of driving is because I'm not meant to.

Leonard: Assuming that everything you say is true, how does the biologically superior Homo Novus get to work tomorrow morning?
Sheldon: Homo Novus doesn't know.
Leonard: Well, hang in there. Maybe you'll evolve into something with wings.

Sheldon: Good morning, gentlemen.
Leonard: Hey.
Raj: Good morning. Is there some new kind of casual Friday I don't know about?
Leonard: No, he lives here now.
Howard: Really? Why?
Leonard: Well, since he won't take the bus and he's too evolved to drive, he decided it would be easier to just sleep in his office and shower in the radiation lab until I'm finished with my experiment.
Raj: But you finished your experiment a week ago.
Leonard: Yep.

Sheldon: I often forget other people have limitations. It's so sad.
Howard: He can feel sadness?
Leonard: Not really. It's what you and I would call condescension.

Howard: Sheldon, don't take this the wrong way, but, you're insane.
Leonard: That may well be, but the fact is it wouldn't kill us to meet some new people.
Sheldon: For the record, it could kill us to meet new people. They could be murderers or the carriers of unusual pathogens. And I'm not insane, my mother had me tested.

(Sheldon smiles in a grotesque way).
Howard: Oh crap that's terrifying.

Sheldon: You know, this situation with Koothrappali brings to mind a story from my childhood.
Howard: Oh, goody, more tales from the Panhandle.
Sheldon: That's Northwest Texas. I'm from East Texas, the Gulf region. Home to many Vietnamese shrimpers.
Leonard: Do the shrimpers feature in your story?
Sheldon: No. Anyway, when I was eight, a Montgomery Ward delivery van ran over our family cat, Lucky.
Howard: Lucky?
Sheldon: Yes, Lucky.
Leonard: He's irony-impaired. Just move on.
Howard: Ok, dead cat named Lucky. Continue.

Raj: Welcome to the Raj Majal.

Raj: Boy, I bet Ellen Page's friends aren't giving her this kind of crap!

Sheldon: Hey! Look I found my missing neutrino.
Howard: Oh, great! We can take it off the milk carton.

Raj: Dr. Gablehouser.
Dr. Gablehouser: Dr. Koothrapali.
Leonard: Dr. Gablehouser.
Dr. Gablehouser: Dr. Hofstadter.
Sheldon: Dr. Gablehouser.
Dr. Gablehouser: Dr. Cooper.
Howard: Dr. Gablehouser.
Dr. Gablehouser: Mr. Wolowitz

Sheldon: In Papua New Guinea, there's a tribe when a hunter flaunts his success to the rest of the village, they kill him and drive away evil spirits with a drum made of his skin. Superstitious nonsense, of course, but one can see their point.

Raj: So, Saturday night. Can I count on my posse?
Howard: Jeez, I'd love to Raj but I can't make it.
Raj: Ah, okay, Leonard?
Leonard: Oh, ah, oh, I can ... no.
Raj: Sheldon?
Sheldon: I can make it but I won't.

Leonard: [to a "smiling" Sheldon] We're here to see Koothrappali, not kill Batman.