Howard: I remember when I was five, hiding under this desk with all my Halloween candy. Had some Peanut M&Ms, went into my first anaphylactic shock and had to be rushed to the hospital. Came home, celebrated with a Snickers, went into my second anaphylactic shock.
Raj: When did you figure out you were allergic to nuts?
Howard: Sometime around the third Almond Joy.

Leonard: Okay. You want to start loading this stuff into the truck?
Howard: Yeah, I guess. Hey, would you do me a favor? Go on ahead. I just want one last moment alone in my old room.
Leonard: We're not standing outside by the U-Haul while you fondle yourself.
Howard: Fine, let's go.

Penny: So what are you drinking?
Sheldon: Well, it’s been a rough day. I usually go chamomile tea, but I don't think that's going to cut it.
Penny: You could have a Long Island Iced Tea.
Sheldon: Will that calm my nerves?
Penny: It's calmed the pants off me a couple of times.
Sheldon: Sold.

Sheldon: Amy deserves better. You know, when we buy the Planter's deluxe mix, she eats all the Brazil nuts so I don't have to look at them. She's a unique blend of saint and squirrel.

Bernadette: Aw, she'll be okay. She's a grown woman.
Howard: I know. It's just ever since my dad left, I've felt responsible for her.
Bernadette: That's a lot for a kid to deal with.
Howard: She was just so sad all the time. I was the only person who could cheer her up. Well, me and Ben and Jerry.
Bernadette: She's lucky you were there.
Howard: You know, she's why I first got into magic. I would do little shows for her, hang up a bedsheet like it was a curtain, put on a top hat and cape. And part way through the act, I would say I needed a volunteer from the audience to be my beautiful assistant and invite her up on stage. I can still remember the way she'd smile. For a few minutes, she'd forget how lonely she was.
Bernadette: Aw, crap. Let's go.
Howard: Where we going?
Bernadette: Grab a box. We'll sleep at your mother's place tonight.
Howard: No, but I want to live here.
Bernadette: Well, you should've thought of that before you told me the stupid magic trick story.

Wil Wheaton: Hey, Sheldon, what's up?
Sheldon: Wouldn't you like to know?
Wil Wheaton: Have you been drinking?
Sheldon: Just tea. S'the best tea I've ever had.
Wil Wheaton: Why are you here?
Sheldon: I'll tell you. I'm from Texas. Need I say more?
Wil Wheaton: Yeah, actually, a little more would be helpful.

Sheldon: You insulted my woman. I'm here to defend her honor. Two! It was two. *Knock, knock, knock* Wil Wheaton! Now prepare yourself for what may come.

Wil Wheaton: Okay, I'm sorry.
Sheldon: Well, that was a long bus ride for not very much.
Wil Wheaton: Are you okay?
Sheldon: You're asking a lot of questions, Wil Wheaton. As a matter of idle curiosity, which of your shrubberies do you feel would benefit from a thorough vomiting? Never mind, I'll choose. (Vomits) You were so good in Stand by Me.

Sheldon: Hello, I'm Dr. Sheldon Cooper. Welcome to Sheldon Cooper Presents Fun with Flags. Get ready for a very special episode where we explore the flags of the popular entertainment franchise, Star Trek. And to help us, I’m pleased to introduce a special guest, surprisingly, it only took gas money and the promise of free food to get him here, Mr. LeVar Burton.
LeVar Burton: Hey, Sheldon, it's a pleasure to be here. Well, we've got some interesting flags for-
Amy: Cut. Yikes, this guy is worse than Wil Wheaton.

Sheldon: I don't know what she's talking about, but I'm obligated to agree with her. She's my girlfriend.
LeVar Burton: Ah, I hear you, brother. I still get lunch, right?

Stephen Hawking: What does Sheldon Cooper and a black hole have in common? They both suck.

Sheldon: Steven Hawking's a genius and he talks like a robot. It's everything I ever wanted in a friend.

Sheldon: I'll be Coop and he'll be Wheels. If he's okay with that.

Leonard: Please be good, please be good. Uh-huh, uh-huh. Okay, she writes like she cooks.

Leonard: I did a bad thing.
Sheldon: Does it affect me?
Leonard: No.
Sheldon: Then suffer in silence.