Amy: It's so nice both of your moms are coming in to see you guys get an award.
Sheldon: Well, my mother's been there for every honor I've won since I beat out my twin sister for the Did It on the Potty trophy.

Sheldon: Leonard's mom is a renowned psychiatrist and woman of science. Can you please keep the Bible babble to yourself while she's here?
Mary Cooper: Are you ashamed of me?
Sheldon: Of course not. I love you. I'm just embarrassed by the things you believe, do and say.
Mary Cooper: Well, I love you, too, my little bowl of lion chow.

Mary Cooper: You must be very proud of your son.
Beverly Hofstadter: Oh, yes. He recently argued a case before the Supreme Court.
Mary Cooper: He did?
Beverly Hofstadter: Oh, you mean this son. Uh, sure, he's terrific.

Leonard: Not once did my mother ever give me any love or affection for just being myself. I always had to earn it.
Mary Cooper: Oh, Leonard, I'm sure she loves you very much. In her own cold godless way.

Mary Cooper: I tried to read your paper, but it was very hard for me to understand.
Sheldon: Oh, it's quite straightforward, actually. It describes a new model of the universe that conceptualizes it as the surface of an n-dimensional superfluid.
Mary Cooper: Interesting. You can believe that, but God filling an ark with animals two-by-two is nonsense.
Sheldon: What did they feed the lions, Mother?
Mary Cooper: The floating bodies of drowned sinners, of course.

Beverly Hofstadter: I'm terribly sorry that I upset your mother.
Sheldon: Oh, it's all right. She'll forgive you. She has to or she goes to hell.

Beverly Hofstadter: Do you suppose you would have flourished more in a more reward-based environment?
Sheldon: Perhaps. But my mom made me spaghetti with chopped up hot dogs whenever I wanted, so who cares.

Amy: Sure, his mom gets roses. When I want them, they're a "bouquet of severed plant genitals."
Sheldon: You act like I didn't get you that mushroom log on Valentine's Day.
Amy: He's right. Roses die, but a moist rotting log will pump out mushrooms for two or three magical years.

Beverly Hofstadter: So, have you and Penny set a wedding date?
Leonard: No, we're kind of taking it slow.
Beverly Hofstadter: I see.
Leonard: What does that mean?
Beverly Hofstadter: You've been on and off with this woman for seven years and engaged for one year. One has to wonder if there's a problem. Are you having satisfactory intercourse?
Leonard: Yes, Mother.
Beverly Hofstadter: Only satisfactory. I see.

Stuart: Bernadette's not wrong. She does work hard around here.
Raj: Yeah, maybe it's a good thing if she stops babying you so much.
Howard: She doesn't baby me.
Stuart: I saw her pull you home in a wagon.
Howard: For your information, I twisted my ankle chasing the ice cream truck.

Beverly Hofstadter: Fascinating. How can someone as enlightened as Sheldon come from someone like you?

Mary Cooper: Shelly does not like change.
Sheldon: True. But all the clenching in the world will not keep testicles in your abdomen.

Leonard: Even with your mother here, you are deliberately hogging all the attention from my mom. You're like one of those elephant seal pups that steals the milk from two mothers!
Sheldon: Do you mean what marine biologists refer to as "super weaning"?
Leonard: Yes, you are a super weaner!

Sheldon: But still, you need to consider how successful Leonard's brother and sister are.
Beverly Hofstadter: I suppose.
Sheldon: While my brother and sister are mouth-breathing idiots.

Howard: It's time for me to act like an adult in this marriage. Starting with my husbandly duty of taking out the trash.
*garbage falls out of the bottom of bag*
Bernie, I made a mess!