Leonard: Next question. Uh, "how close are you with your family?"
Penny: Pretty close.
Leonard: I'm gonna say not too close, but I'm hoping to get farther.

Leonard: Hang on. Are you feeling insecure? Because that's my thing, and if you take it away, I don't know what I'm bringing to this relationship.

Penny: Where's Sheldon?
Leonard: Oh, he was up late last night, so I gave him an early dinner and put him to bed.
Bernadette: That's so sweet.
Leonard: Yeah, but now he's gonna be up at dawn and want to play.

Howard: That was weird, right?
Leonard: Was it? I honestly can't tell anymore.

Leonard: You see, I used to be a jackass, but I stopped myself. I became a good guy. See, that's kind of my superpower. I'm like Captain Good Guy!
(Alice pushes him out, then slams door)
Leonard: It's okay. Did the right thing. *tightens his jacket* You idiot!

Priya: It's a little weird your ex-girlfriend hanging out here all the time.
Leonard: I know. I usually never see my ex-girlfriends, unless their hard drives crash.

Raj: I'm thinking about adopting some quirky affectation, like a pipe or a monocle or a handlebar moustache.
Leonard: For all those girls out there looking for the Indian Monopoly man?

Beverly Hofstadter: Penny, I hope the example of my failed marriage to Leonard's father doesn't discourage you from the commitment you've made to one another.
Penny: No, of course not.
Beverly Hofstadter: Although Alfred and I had a lot more going for us than you two.
Leonard: Mom, please save something for the toast.

Beverly Hofstadter: How dare you invite your father without consulting me.
Leonard: Sorry, but I don't think I need your permission to have my father at my wedding.
Beverly Hofstadter: You do understand our marriage ended because he had an affair.
Leonard: I know, and there's no excuse for that.
Beverly Hofstadter: He claimed I was cold, emasculating, and hadn't shown him any physical affection for years.
Leonard: I was wrong, there's three excuses for that.

Leonard: I got all your favorites. Beer, wings, sliders. We can watch the football game. I even painted my stomach.
Penny: Go Sports?
Leonard: Well, in case you were in the mood for baseball, I didn't want to look ridiculous.

Leonard: Listen, Sheldon, this is stupid. I don't see why we can't be friends. And I'm willing to drive you around and help you out with stuff. I just don't want to do it because of some silly roommate agreement.
Sheldon: What are you proposing?
Leonard: That we go back to the way things were. But when I do something for you, you show a little appreciation.
Sheldon: And how would I do that?
Leonard: You say thank you.
Sheldon: Every time?
Leonard: It's not crazy.

Sheldon: Now, Penny, we don't consume alcohol during Dungeons and Dragons. It impairs our judgment.
Penny: Oh, this isn't alcohol. It's a magic potion that makes me like you.
Leonard: Double potion, please.

Penny: The pastrami truck moved.
Leonard: That is the danger of a restaurant on wheels.

Howard: You look like you come with a kickstand.
Raj: You can't make me feel bad.
Howard: Hmm, maybe not. Leonard?
Leonard: So, when the aliens brought you back, they just left the probe in?

Leonard: I never wanted to play the cello. How do you meet girls playing the cello? Hey, you want to come over to my house and listen to me play an instrument that sounds like a suicidal bumblebee?