Penny: So, do you know who's in there?
Sheldon: Well, there's Leonard. ... (Picking up violin case) And he's either with Leslie Winkle or a 1930s gangster.

Penny: Alright, look, a tie on the doorknob usually means someone doesn't want to be disturbed because they’re, you know, getting busy.
Sheldon: So you're saying Leonard has a girl in there.
Penny: Well, either that or he's lost his tie rack and gotten really into Bryan Adams.

Sheldon: Do you realise I may have to share a Nobel Prize with your booty call?
Leonard: You know what, I'm being ridiculous. Who cares what Penny thinks? Leslie is a terrific girl. She's attractive, we like each other, she's extremely intelligent.
Sheldon: She's not that intelligent.
Leonard: She fixed your equation.
Sheldon: She got lucky.
Leonard: You don't believe in luck.
Sheldon: I don't have to believe in it for her to be lucky.

Leonard: What did Penny mean, you'd make a cute couple?
Sheldon: Well I assume she meant that the two of you together would constitute a couple that others might consider cute. An alternate, and somewhat less likely interpretation, is that you could manufacture one. As in, oh look, Leonard and Leslie made Mr. and Mrs. Goldfarb, aren't they adorable.

Sheldon: Alright, I'm moving my infantry division, augmented by a battalion of Orcs from Lord of the Rings, we flank the Tennessee Volunteers, and the North once again wins the Battle of Gettysburg.
Howard: Not so fast, remember the South still has two infantry divisions, plus Superman and Godzilla.
Leonard: No, no, no, no, Orcs are magic, Superman is vulnerable to magic, not to mention, you already lost Godzilla to the Illinois Cavalry and Hulk.
Raj: Why don't you just have Robert E. Lee charge the line with Shiva and Ganesh?

Howard: Hang on, honey. Shiva and Ganesh? The Hindu Gods against the entire Union army?
Leonard: And Orcs!
Penny: I'll be back.
Raj: Excuse me, Ganesh is the remover of obstacles, and Shiva is the destroyer. When the smoke clears, Abraham Lincoln will be speaking Hindi and drinking mint juleps.

Howard: I'll take the heart smart platter.
Penny: Alright, thank you, and Sheldon.
Sheldon: We don't eat here. I don't know what's good.
Penny: Well, it's all good.
Sheldon: Statistically unlikely.

Raj: Oh dear.
Howard: What's the matter?
Raj: She didn't take my order.
Howard: How can she take your order when you're too neurotic to talk to her?
Raj: Nevertheless, this will be reflected in her tip.

Leonard: You cannot possibly be that arrogant.
Sheldon: You continue to underestimate me, my good man.

Sheldon: As I have explained repeatedly, unlike you, I don't need validation from lesser minds. No offense.
Leonard: Really, so why did you come?
Sheldon: Because I knew you’d screw this up.
Leonard: I didn't screw it up.
Sheldon: Oh, please. I admit, that spherical chicken joke, that was hilarious. But it was straight downhill from there.

Penny: Is this your only tie?
Leonard: Ah. Technically yes, but, if you'll notice, it's reversible. So it works as two.
Penny: Oh, sweetie, I don't think it even works as one.

Sheldon: Were you trying to impress Penny?
Leonard: No, no not at all. ... A little bit.
Sheldon: How'd that work out for you?
Penny: (entering the apartment) Leonard, ready to go?
Sheldon: Libido 1, Truth 0.

Penny: Anyway, I was talking to Leonard this morning and I think he feels really bad about it.
Sheldon: Huh.
Penny: Well, how do you feel?
Sheldon: I don't understand the question.
Penny: Well I'm just asking if it's difficult to be fighting with your best friend.
Sheldon: Oh. I hadn't thought about it like that. I wonder if I've been experiencing physiological manifestations of some sort of unconscious emotional turmoil.
Penny: Wait, what?
Sheldon: I couldn't poop this morning.

Penny: You should just talk to him, I'm sure you guys can work this out.
Sheldon: It's certainly preferable to my plan.
Penny: Which was?
Sheldon: A powerful laxative.

Penny: So you and Leonard-
Sheldon: Oh dear God.
Penny: Little misunderstanding, huh?
Sheldon: A little misunder- Galileo and the Pope had a little misunderstanding.