Sheldon: How dare you.
Amy: Oh, you heard me. Your experimental bona fides are laughable.
Sheldon: Whoa, whoa! Now you're making fun of my bona fides?
Amy: Can't make fun of something that's a null set.
Penny: I feel like I should say "damn!"
Leonard: Do it.
Penny: Damn!

Sheldon: Well, if you are so protective of the scientific method, perhaps we should use the next five weeks to finish what we started.
Amy: Well, for science, maybe I will!
Sheldon: For science, maybe you should!
Amy: Fine!
Sheldon: Fine!
Amy: Good.
Sheldon: Great.
Amy: Do you want to go to our place and make out?
Sheldon: Does Stephen Hawking roll through the quad?

Penny: Now Sheldon's popular? What is happening?!

Sheldon: I am cool. This is YooHoo. Chocolate milk's delicious, watery cousin.

Bernadette: I'm clearly upset. Why aren't you following me?

Penny: It's okay, I'll still go.
Leonard: You don't think you'll be bored?
Penny: Oh, I'll have some wine and listen to people go on about crap I don't understand. I mean, how is it any different than every single day of my life?
Sheldon: I won't be there.
Leonard: Look at that, it is a party!

Sheldon: I am facing a great deal of work. And I do like things better when famous people also like them.

Raj: Well, I think the first thing we should get rid of is that tone.

Bernadette: Sorry I flipped out on you. I think it's just hormones.
Raj: I think you were mean before you were pregnant, but it's fine.

Sheldon: No, I know, but plenty of things are addictive after a single exposure. I mean, crack cocaine, nicotine, Pringles. You know, once one pops one just can't stop.

Howard: It's pretty late. You think I've got time to run some more simulations on the cooling system?
Leonard: Sure, I'm still figuring out the thermo-acoustic expander.
Sheldon: Oh, while you do that I am going to pump cerebral spinal fluid through my brain cells to remove the metabolic by-products of the day's thoughts.
Howard: What?
Sheldon: It's called sleep and it's my bedtime. Nighty-night, y'all.

Howard: Hey, hey, hey, you're not going anywhere.
Leonard: We only have two months to deliver this to the Air Force because of you.
Sheldon: (yawning) I know, I was there.
Howard: Well, wake up! We're gonna put in a lot of late nights.
Sheldon: How late?
Howard: Well, I don't know, midnight, one.
Sheldon: One o'clock? I'm not a raccoon.

Howard: If you're tired, have some coffee.
Sheldon: What? You have some coffee.
Howard: I am having coffee.
Sheldon: And look how irritable it's making you!

Sheldon: I don't think I can go much longer.
Leonard: It's been three and a half minutes, wake up!

Sheldon: I had a bad dream that my best friend became a tyrant and forced me to stay up all night to work.
Leonard: I had a good dream that when I carried you to bed, I let your head hit the wall and I laughed.